Nanotechnology has been increasingly utilized in anticancer treatment owing to its ability of
engineering functional nanocarriers that enhance therapeutic effectiveness while minimizing …

This comprehensive review delves into the pivotal role of the tumor microenvironment (TME)
in cancer metastasis and therapeutic response, offering fresh insights into the intricate …

Mesenchymal stem cells (MSCs) in tumor microenvironment (TME) are crucial for the
initiation, development, and metastasis of cancer. The impact and mechanism of MSCs on …

Introduction Cancer development and progression is a complex process influenced by co-
evolution of the cancer cells and their microenvironment. However, traditional anti-cancer …

Navigating the intricate landscape of the tumor microenvironment (TME) unveils a pivotal
arena for cancer therapeutics, where cytokines and soluble mediators emerge as double …

Chimeric antigen receptor (CAR) T cell therapy has emerged as a groundbreaking treatment
for hematological cancers, yet it faces significant hurdles, particularly regarding its efficacy in …

Background T cell exhaustion in the tumor microenvironment has been demonstrated as a
substantial contributor to tumor immunosuppression and progression. However, the …

Cytarabine, an antimetabolite antineoplastic agent, has been utilized to treat various
cancers. However, because of its short half-life, low stability, and limited bioavailability …

Cancer stem cells are the key link between malignant tumor progression and drug
resistance. This cell population has special properties that are different from those of …

The tumor microenvironment (TME) is integral to cancer progression, impacting metastasis
and treatment response. It consists of diverse cell types, extracellular matrix components …