Major depressive disorder: advances in neuroscience research and translational applications

Z Li, M Ruan, J Chen, Y Fang - Neuroscience bulletin, 2021 - Springer
Major depressive disorder (MDD), also referred to as depression, is one of the most common
psychiatric disorders with a high economic burden. The etiology of depression is still not …

Toward clinical digital phenoty**: a timely opportunity to consider purpose, quality, and safety

K Huckvale, S Venkatesh, H Christensen - NPJ digital medicine, 2019 - nature.com
The use of data generated passively by personal electronic devices, such as smartphones,
to measure human function in health and disease has generated significant research …

Predicting treatment outcomes in major depressive disorder using brain magnetic resonance imaging: a meta-analysis

F Long, Y Chen, Q Zhang, Q Li, Y Wang, Y Wang… - Molecular …, 2024 - nature.com
Recent studies have provided promising evidence that neuroimaging data can predict
treatment outcomes for patients with major depressive disorder (MDD). As most of these …

Functional MRI in major depressive disorder: A review of findings, limitations, and future prospects

J Pilmeyer, W Huijbers, R Lamerichs… - Journal of …, 2022 - Wiley Online Library
Objective diagnosis and prognosis in major depressive disorder (MDD) remains a challenge
due to the absence of biomarkers based on physiological parameters or medical tests …

[HTML][HTML] MRI predictors of pharmacotherapy response in major depressive disorder

AR Gerlach, HT Karim, M Pecina, O Ajilore… - NeuroImage: Clinical, 2022 - Elsevier
Major depressive disorder is among the most prevalent psychiatric disorders, exacting a
substantial personal, social, and economic toll. Antidepressant treatment typically involves …

An integrative way for studying neural basis of basic emotions with fMRI

S Gu, F Wang, C Cao, E Wu, YY Tang… - Frontiers in …, 2019 - frontiersin.org
How emotions are represented in the nervous system is a crucial unsolved problem in the
affective neuroscience. Many studies are striving to find the localization of basic emotions in …

Prediction of remission among patients with a major depressive disorder based on the resting-state functional connectivity of emotion regulation networks

H Wu, R Liu, J Zhou, L Feng, Y Wang, X Chen… - Translational …, 2022 - nature.com
The prediction of antidepressant response is critical for psychiatrists to select the initial
antidepressant drug for patients with major depressive disorders (MDD). The implicated …

Intrinsic brain network biomarkers of antidepressant response: a review

K Dunlop, A Talishinsky, C Liston - Current psychiatry reports, 2019 - Springer
Abstract Purpose of Review Poor treatment response is a hallmark of major depressive
disorder. To tackle this problem, recent neuroimaging studies have sought to characterize …

Magnetic resonance imaging for individual prediction of treatment response in major depressive disorder: a systematic review and meta-analysis

SE Cohen, JB Zantvoord, BN Wezenberg… - Translational …, 2021 - nature.com
No tools are currently available to predict whether a patient suffering from major depressive
disorder (MDD) will respond to a certain treatment. Machine learning analysis of magnetic …

Predicting differential diagnosis between bipolar and unipolar depression with multiple kernel learning on multimodal structural neuroimaging

B Vai, L Parenti, I Bollettini, C Cara, C Verga… - European …, 2020 - Elsevier
One of the greatest challenges in providing early effective treatment in mood disorders is the
early differential diagnosis between major depression (MDD) and bipolar disorder (BD). A …