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Antibiotic perturbations to the gut microbiome
Antibiotic-mediated perturbation of the gut microbiome is associated with numerous
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
infectious and autoimmune diseases of the gastrointestinal tract. Yet, as the gut microbiome …
Genomics and pathotypes of the many faces of Escherichia coli
J Geurtsen, M de Been, E Weerdenburg… - FEMS microbiology …, 2022 - academic.oup.com
Escherichia coli is the most researched microbial organism in the world. Its varied impact on
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …
human health, consisting of commensalism, gastrointestinal disease, or extraintestinal …
Validating the AMRFinder tool and resistance gene database by using antimicrobial resistance genotype-phenotype correlations in a collection of isolates
M Feldgarden, V Brover, DH Haft… - Antimicrobial agents …, 2019 - journals.asm.org
Antimicrobial resistance (AMR) is a major public health problem that requires publicly
available tools for rapid analysis. To identify AMR genes in whole-genome sequences, the …
available tools for rapid analysis. To identify AMR genes in whole-genome sequences, the …
Sequencing-based methods and resources to study antimicrobial resistance
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …
Machine learning for antimicrobial resistance prediction: current practice, limitations, and clinical perspective
Antimicrobial resistance (AMR) is a global health crisis that poses a great threat to modern
medicine. Effective prevention strategies are urgently required to slow the emergence and …
medicine. Effective prevention strategies are urgently required to slow the emergence and …
MEGARes 2.0: a database for classification of antimicrobial drug, biocide and metal resistance determinants in metagenomic sequence data
Antimicrobial resistance (AMR) is a threat to global public health and the identification of
genetic determinants of AMR is a critical component to epidemiological investigations. High …
genetic determinants of AMR is a critical component to epidemiological investigations. High …
Using genomics to track global antimicrobial resistance
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
revolutionized diagnostic microbiology and microbial surveillance. The availability of …
Innovative and rapid antimicrobial susceptibility testing systems
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …
detection and quantification of resistance, combined with antimicrobial stewardship, are key …
DeepARG: a deep learning approach for predicting antibiotic resistance genes from metagenomic data
Background Growing concerns about increasing rates of antibiotic resistance call for
expanded and comprehensive global monitoring. Advancing methods for monitoring of …
expanded and comprehensive global monitoring. Advancing methods for monitoring of …
Next-generation approaches to understand and combat the antibiotic resistome
Antibiotic resistance is a natural feature of diverse microbial ecosystems. Although recent
studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …
studies of the antibiotic resistome have highlighted barriers to the horizontal transfer of …