Parkinson disease (PD) is the second most common neurodegenerative disorder, affecting>
1% of the population≥ 65 years of age and with a prevalence set to double by 2030. In …

Neurodegenerative diseases are a common cause of morbidity and cognitive impairment in
older adults. Most clinicians who care for the elderly are not trained to diagnose these …

Idiopathic REM sleep behaviour disorder (iRBD) is a powerful early sign of Parkinson's
disease, dementia with Lewy bodies, and multiple system atrophy. This provides an …

Background and Objectives Short-chain fatty acids (SCFAs) are gut microbial metabolites
that promote the disease process in a rodent model of Parkinson disease (PD), but fecal …

Background Although several studies have suggested that abnormalities in gut microbiota
may play a critical role in the pathogenesis of PD, data are still extremely heterogeneous …

The clinical features of dementia with Lewy bodies (DLB) and Parkinson's disease dementia
(PDD) are similar and include dementia, cognitive fluctuations, and (visual) hallucinations in …

Dynamic functional connectivity captures temporal variations of functional connectivity
during MRI acquisition and it may be a suitable method to detect cognitive changes in …

Parkinson's disease (PD) is the second most common neurodegenerative disease after
Alzheimer's. PD is considered a multifactorial disorder that results, in most cases, from the …

Non-motor symptoms (NMS) of Parkinson's disease can be predominant as the disease
advances, thereby constituting a major source of disease burden for patients and caregivers …

Importance There is increasing evidence that Parkinson disease (PD) is heterogeneous in
its clinical presentation and prognosis. Defining subtypes of PD is needed to better …