Oligodendrocytes generate multiple layers of myelin membrane around axons of the central
nervous system to enable fast and efficient nerve conduction. Until recently, saltatory nerve …

Myelin, a lipid membrane that wraps axons, enabling fast neurotransmission and metabolic
support to axons, is conventionally thought of as a static structure that is set early in …

Oligodendrocyte progenitor cells (OPCs), which differentiate into myelinating
oligodendrocytes during CNS development, are the main proliferative cells in the adult …

Introduction Myelin is formed by mature oligodendrocytes to facilitate fast propagation of
action potentials in axons. Small changes in myelin thickness can confer substantial …

Oligodendrocytes make myelin and support axons metabolically with lactate. However, it is
unknown how glucose utilization and glycolysis are adapted to the different axonal energy …

Oligodendrocyte precursor cells (OPCs) originate in the ventricular zones (VZs) of the brain
and spinal cord and migrate throughout the develo** central nervous system (CNS) …

Oligodendrocytes are glial cells that populate the entire CNS after they have differentiated
from oligodendrocyte progenitor cells. From birth onward, oligodendrocytes initiate wrap** …

Reciprocal interactions between neurons and oligodendrocytes are not only crucial for
myelination, but also for long-term survival of axons. Degeneration of axons occurs in …

An essential feature of vertebrate neural development is ensheathment of axons with myelin,
an insulating membrane formed by oligodendrocytes. Not all axons are myelinated, but …

Activity-dependent myelination is thought to contribute to adaptive neurological function.
However, the mechanisms by which activity regulates myelination and the extent to which …