The plasma membrane of eukaryotic cells is not a simple sheet of lipids and proteins but is
differentiated into subdomains with crucial functions. Caveolae, small pits in the plasma …

Caveolae are abundant surface pits formed by the assembly of cytoplasmic proteins on a
platform generated by caveolin integral membrane proteins and membrane lipids. This …

The ConSurf web‐sever for the analysis of proteins, RNA, and DNA provides a quick and
accurate estimate of the per‐site evolutionary rate among homologues. The analysis reveals …

Membrane-sculpting proteins shape the morphology of cell membranes and facilitate
remodeling in response to physiological and environmental cues. Complexes of the …

Over the past decade, interest in caveolae biology has peaked. These small bulb-shaped
plasma membrane invaginations of 50–80 nm diameter present in most cell types have …

Caveolae are 70–100 nm diameter plasma membrane invaginations found in abundance in
adipocytes, endothelial cells, myocytes, and fibroblasts. Their bulb-shaped membrane …

Lipid droplets (LDs) are intracellular oil-in-water emulsion droplets, covered by a
phospholipid monolayer and mainly present in the cytosol. Despite their important role in …

Agonist-induced endocytosis is a key regulatory mechanism for controlling the
responsiveness of the cell by changing the density of cell surface receptors. In addition to …

Abstract Caveolin-1 (CAV1) is commonly considered to function as a cell surface protein, for
instance in the genesis of caveolae. Nonetheless, it is also present in many intracellular …

Caveolins (Cavs) are~ 20 kDa scaffolding proteins that assemble as oligomeric complexes
in lipid raft domains to form caveolae, flask-shaped plasma membrane (PM) invaginations …