Most sensory, cognitive and motor functions depend on the interactions of many neurons. In
recent years, there has been rapid development and increasing use of technologies for …

Advances in optical manipulation and observation of neural activity have set the stage for
widespread implementation of closed-loop and activity-guided optical control of neural …

Brain-computer interfaces (BCIs) have the potential to restore communication for people with
tetraplegia and anarthria by translating neural activity into control signals for assistive …

Objective. An important goal of neuroprosthetic research is to establish bidirectional
communication between the user and new prosthetic limbs that are capable of controlling> …

We consider the problem of extracting smooth low-dimensional neural trajectories''that
summarize the activity recorded simultaneously from tens to hundreds of neurons on …

Neocortical activity is permeated with endogenously generated fluctuations, but how these
dynamics affect goal-directed behavior remains a mystery. We found that ensemble neural …

It is generally thought that skilled behavior in human beings results from a functional
hierarchy of the motor control system, within which reusable motor primitives are flexibly …

Advances in our understanding of brain function, along with the development of neural
interfaces that allow for the monitoring and activation of neurons, have paved the way for …

Experiments on humans and other animals have shown that uncertainty due to unreliable or
incomplete information affects behavior. Recent studies have formalized uncertainty and …

Cortical neurons emit seemingly erratic trains of action potentials or “spikes,” and neural
network dynamics emerge from the coordinated spiking activity within neural circuits. These …