Zebrafish have several advantages compared to other vertebrate models used in modeling
human diseases, particularly for large-scale genetic mutant and therapeutic compound …

The burden of cardiovascular and metabolic diseases worldwide is staggering. The
emergence of systems approaches in biology promises new therapies, faster and cheaper …

There is an urgency to find new treatment strategies that could prevent or delay the onset or
progression of AMD. Different classes of lipids and lipoproteins metabolism genes have …

The pathogeneses of the 2 major forms of diabetes, type 1 and type 2, differ with respect to
their major molecular insults (loss of immune tolerance and onset of tissue insulin …

The role of lipids in providing energy and structural cellular components during vertebrate
development is poorly understood. To elucidate these roles further, we visualized lipid …

The zebrafish (Danio rerio) has emerged as an appreciated and versatile model organism
for studying cardiovascular and metabolic diseases, offering unique advantages for both …

While the field of epigenetics is increasingly recognized to contribute to the emergence of
phenotypes in mammalian research models across different developmental and …

The zebrafish (Danio rerio) has become a widely used vertebrate model for bacterial, fungal,
viral, and protozoan infections. Due to its genetic tractability, large clutch sizes, ease of …

The zebrafish has emerged as a powerful vertebrate model for studying liver‐associated
disorders. Liver damage is a crucial problem in the process of drug development and …

Nutrition is paramount in sha** all aspects of animal biology. In addition, the influence of
the intestinal microbiota on physiology is now widely recognized. Given that diet also …