Wastewater is among the most important reservoirs of antibiotic resistance in urban
environments. The abundance of carbon sources and other nutrients, a variety of possible …

Antibiotic resistance (AR) is a global problem requiring international cooperation and
coordinated action. Global monitoring must rely on methods available and comparable …

Background There is concern that the microbially rich activated sludge environment of
wastewater treatment plants (WWTPs) may contribute to the dissemination of antibiotic …

Shotgun metagenomic sequencing of the collective genomic information carried across
microbial communities is emerging as a powerful approach for monitoring antibiotic …

Antimicrobial resistance (AMR), a cross-cutting and increasing threat to global health (1–3),
is a complex problem with multiple and interconnected drivers. Reliable surveillance data …

Water environments are increasingly recognized as a conduit for the spread of antibiotic
resistance, but there is need to standardize antibiotic resistance monitoring protocols to …

This Opinion considers the application of whole genome sequencing (WGS) and
metagenomics for outbreak investigation, source attribution and risk assessment of food …

Antimicrobial resistance (AMR) surveillance is a critical step within risk assessment
schemes, as it is the basis for informing global strategies, monitoring the effectiveness of …

In the fight to limit the global spread of antibiotic resistance, the assembly of environmental
metagenomes has the potential to provide rich contextual information (eg, taxonomic hosts …

Background Direct and indirect selection pressures imposed by antibiotics and co-selective
agents and horizontal gene transfer are fundamental drivers of the evolution and spread of …