Giant vesicles as cell models

SF Fenz, K Sengupta - Integrative Biology, 2012 - academic.oup.com
Tremendous progress has been made in recent years in understanding the working of the
living cell, including its micro-anatomy, signalling networks, and regulation of genes …

Physics of cell adhesion: some lessons from cell-mimetic systems

E Sackmann, AS Smith - Soft matter, 2014 - pubs.rsc.org
Cell adhesion is a paradigm of the ubiquitous interplay of cell signalling, modulation of
material properties and biological functions of cells. It is controlled by competition of short …

Measuring shape fluctuations in biological membranes

C Monzel, K Sengupta - Journal of Physics D: Applied Physics, 2016 - iopscience.iop.org
Shape fluctuations of lipid membranes have intrigued cell biologists and physicists alike. In
the cellular context, their origin—thermal or active—and their physiological significance are …

Membrane fluctuations mediate lateral interaction between cadherin bonds

SF Fenz, T Bihr, D Schmidt, R Merkel, U Seifert… - Nature physics, 2017 - nature.com
The integrity of living tissues is maintained by adhesion domains of trans-bonds formed
between cadherin proteins residing on opposing membranes of neighbouring cells. These …

Polymer time crystal: Mechanical activation of reversible bonds by low-amplitude high frequency excitations

M Heidari, T Gaichies, L Leibler, M Labousse - Science Advances, 2024 - science.org
Reversible supramolecular bonds play an important role in materials science and in
biological systems. The equilibrium between open and closed bonds and the association …

First-principle coarse-graining framework for scale-free bell-like association and dissociation rates in thermal and active systems

JA Janeš, C Monzel, D Schmidt, R Merkel, U Seifert… - Physical Review X, 2022 - APS
Fluctuations of surfaces that harbor reactive molecules interacting across the intervening
space strongly influence the reaction kinetics. One such paradigmatic system is the cell …

Nucleation of ligand-receptor domains in membrane adhesion

T Bihr, U Seifert, AS Smith - Physical review letters, 2012 - APS
We present a comprehensive model for the nucleation of domains in membrane adhesion.
We determine the critical number of bonds in a nucleus and calculate the probability …

Model system for cell adhesion mediated by weak carbohydrate–carbohydrate interactions

B Lorenz, L Alvarez de Cienfuegos… - Journal of the …, 2012 - ACS Publications
The multivalent carbohydrate–carbohydrate interaction between membrane-anchored
epitopes derived from the marine sponge Microciona prolifera has been explored by …

Multiscale approaches to protein-mediated interactions between membranes—relating microscopic and macroscopic dynamics in radially growing adhesions

T Bihr, U Seifert, AS Smith - New journal of physics, 2015 - iopscience.iop.org
Macromolecular complexation leading to coupling of two or more cellular membranes is a
crucial step in a number of biological functions of the cell. While other mechanisms may also …

Mimicking adhesion in minimal synthetic cells

SM Bartelt, E Chervyachkova, J Ricken… - Advanced …, 2019 - Wiley Online Library
Cell adhesions to the extracellular matrix and to neighboring cells are fundamental to cell
behavior and have also been implemented into minimal synthetic cells, which are …