Physiopathology of spine metastasis

G Maccauro, MS Spinelli, S Mauro… - … journal of surgical …, 2011 - Wiley Online Library
The metastasis is the spread of cancer from one part of the body to another. Two‐thirds of
patients with cancer will develop bone metastasis. Breast, prostate and lung cancer are …

Neutrophil gelatinase-associated lipocalin (NGAL), pro-matrix metalloproteinase-9 (pro-MMP-9) and their complex pro-MMP-9/NGAL in leukaemias

S Bouchet, B Bauvois - Cancers, 2014 - mdpi.com
Matrix metalloproteinase (MMP)-9 and neutrophil gelatinase-associated lipocalin (NGAL)
have gained attention as cancer biomarkers. The inactive zymogen form of MMP-9 (pro …

Endothelial cells in the bone marrow of patients with multiple myeloma

A Vacca, R Ria, F Semeraro, F Merchionne, M Coluccia… - Blood, 2003 - ashpublications.org
Endothelial cells (EC) were extracted through a lectin-based method from bone marrow of
57 patients with active multiple myeloma (MM) and compared with their healthy quiescent …

The effects of cold atmospheric plasma on cell adhesion, differentiation, migration, apoptosis and drug sensitivity of multiple myeloma

D Xu, X Luo, Y Xu, Q Cui, Y Yang, D Liu, H Chen… - Biochemical and …, 2016 - Elsevier
Cold atmospheric plasma was shown to induce cell apoptosis in numerous tumor cells.
Recently, some other biological effects, such as induction of membrane permeation and …

Production of matrix metalloproteinase-9 in early stage B-CLL: suppression by interferons

B Bauvois, J Dumont, C Mathiot, JP Kolb - Leukemia, 2002 - nature.com
Besides vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF),
matrix metalloproteinases (MMPs) play critical roles in angiogenesis, tumor invasion and …

New horizons in our understanding of precursor multiple myeloma and early interception

DM Cordas dos Santos, R Toenges, L Bertamini… - Nature Reviews …, 2024 - nature.com
Multiple myeloma is an incurable plasma cell malignancy that evolves over decades through
the selection and malignant transformation of monoclonal plasma cells. The evolution from …

Extracellular matrix and the myeloid-in-myeloma compartment: balancing tolerogenic and immunogenic inflammation in the myeloma niche

F Asimakopoulos, C Hope, MG Johnson… - Journal of leukocyte …, 2017 - academic.oup.com
The last 10–15 years have witnessed a revolution in treating multiple myeloma, an incurable
cancer of Ab-producing plasma cells. Advances in myeloma therapy were ushered in by …

N-Myc and Bcl-2 coexpression induces MMP-2 secretion and activation in human neuroblastoma cells

D Noujaim, CM van Golen, KL van Golen, A Grauman… - Oncogene, 2002 - nature.com
Neuroblastoma is a peripheral nervous system tumor that accounts for 8–10% of all solid
childhood tumors. N-Myc is the most reliable prognostic indicator for neuroblastoma. Bcl-2 is …

O-GlcNAcylation homeostasis controlled by calcium influx channels regulates multiple myeloma dissemination

P Samart, S Luanpitpong, Y Rojanasakul… - Journal of Experimental …, 2021 - Springer
Background Multiple myeloma (MM) cell motility is a critical step during MM dissemination
throughout the body, but how it is regulated remains largely unknown. As hypercalcemia is …

Overexpression of tetraspanins affects multiple myeloma cell survival and invasive potential

T Tohami, L Drucker, H Shapiro, J Radnay… - The FASEB …, 2007 - Wiley Online Library
Cellular interactions with microenviron‐mental components are critical in multiple myeloma
(MM) and impede effective disease treatment. Mem‐branal‐embedded tetraspanins …