Efficacy of covid-19 vaccines in immunocompromised patients: systematic review and meta-analysis

ARYB Lee, SY Wong, LYA Chai, SC Lee, MX Lee… - Bmj, 2022 - bmj.com
Objective To compare the efficacy of covid-19 vaccines between immunocompromised and
immunocompetent people. Design Systematic review and meta-analysis. Data sources …

COVID-19 vaccine development: milestones, lessons and prospects

M Li, H Wang, L Tian, Z Pang, Q Yang… - Signal transduction and …, 2022 - nature.com
With the constantly mutating of SARS-CoV-2 and the emergence of Variants of Concern
(VOC), the implementation of vaccination is critically important. Existing SARS-CoV-2 …

Intramuscular AZD7442 (tixagevimab–cilgavimab) for prevention of Covid-19

MJ Levin, A Ustianowski, S De Wit… - … England Journal of …, 2022 - Mass Medical Soc
Background The monoclonal-antibody combination AZD7442 is composed of tixagevimab
and cilgavimab, two neutralizing antibodies against severe acute respiratory syndrome …

Risk prediction of covid-19 related death and hospital admission in adults after covid-19 vaccination: national prospective cohort study

J Hippisley-Cox, CAC Coupland, N Mehta, RH Keogh… - bmj, 2021 - bmj.com
Objectives To derive and validate risk prediction algorithms to estimate the risk of covid-19
related mortality and hospital admission in UK adults after one or two doses of covid-19 …

Effect of immunosuppression on the immunogenicity of mRNA vaccines to SARS-CoV-2: a prospective cohort study

P Deepak, W Kim, MA Paley, M Yang… - Annals of internal …, 2021 - acpjournals.org
Background: Patients with chronic inflammatory disease (CID) treated with
immunosuppressive medications have increased risk for severe COVID-19. Although mRNA …

Immunological and clinical efficacy of COVID-19 vaccines in immunocompromised populations: a systematic review

S Galmiche, LBL Nguyen, E Tartour… - Clinical Microbiology …, 2022 - Elsevier
Background Available data show that COVID-19 vaccines may be less effective in
immunocompromised populations, who are at increased risk of severe COVID-19 …

Response to SARS-CoV-2 vaccination in immune mediated inflammatory diseases: systematic review and meta-analysis

A Jena, S Mishra, P Deepak, P Kumar-M, A Sharma… - Autoimmunity …, 2022 - Elsevier
Objectives The treatment for COVID-19 often utilizes immune-modulating drugs. These
drugs are also used in immune mediated inflammatory diseases (IMIDs). We performed a …

COVID-19 vaccine-induced antibody responses in immunosuppressed patients with inflammatory bowel disease (VIP): a multicentre, prospective, case-control study

JL Alexander, NA Kennedy, H Ibraheim… - The lancet …, 2022 - thelancet.com
Background The effects that therapies for inflammatory bowel disease (IBD) have on
immune responses to SARS-CoV-2 vaccination are not yet fully known. Therefore, we …

The effect of methotrexate and targeted immunosuppression on humoral and cellular immune responses to the COVID-19 vaccine BNT162b2: a cohort study

SK Mahil, K Bechman, A Raharja… - The Lancet …, 2021 - thelancet.com
Background Patients on therapeutic immunosuppressants for immune-mediated
inflammatory diseases were excluded from COVID-19 vaccine trials. We therefore aimed to …

Antibody development after COVID-19 vaccination in patients with autoimmune diseases in the Netherlands: a substudy of data from two prospective cohort studies

L Boekel, M Steenhuis, F Hooijberg… - The Lancet …, 2021 - thelancet.com
Background Data are scarce on immunogenicity of COVID-19 vaccines in patients with
autoimmune diseases, who are often treated with immunosuppressive drugs. We aimed to …