Protein language models are biased by unequal sequence sampling across the tree of life

F Ding, J Steinhardt - BioRxiv, 2024 - biorxiv.org
Protein language models (pLMs) trained on large protein sequence databases have been
used to understand disease and design novel proteins. In design tasks, the likelihood of a …

[HTML][HTML] Metabolism of Tryptophan, Glutamine, and Asparagine in Cancer Immunotherapy—Synergism or Mechanism of Resistance?

K Kiełbowski, E Bakinowska, R Becht, A Pawlik - Metabolites, 2025 - mdpi.com
Amino acids are crucial components of proteins, key molecules in cellular physiology and
homeostasis. However, they are also involved in a variety of other mechanisms, such as …