Inbreeding depression, the reduction of fitness caused by inbreeding, is a nearly universal
phenomenon that depends on past mutation, selection, and genetic drift. Recent estimates …

Our ability to assess the threat posed by the genetic load to small and declining populations
has been greatly improved by advances in genome sequencing and computational …

Since allozymes were first used to assess genetic diversity in the 1960s and 1970s,
biologists have attempted to characterize gene pools and conserve the diversity observed in …

Genetic rescue–ameliorating inbreeding depression and restoring genetic diversity of inbred
populations through gene flow-is valuable in wildlife conservation. Empirically validated …

Human activity has caused dramatic population declines in many wild species. The resulting
bottlenecks have a profound impact on the genetic makeup of a species with unknown …

Despite its recognised importance for species' persistence, integrating genetics into
conservation management has proved problematic, creating a “conservation genetics gap” …

Conservation breeding programs such as zoos play a major role in preventing extinction, but
their sustainability may be impeded by neutral and adaptive population genetic change …

Genomes retain evidence of the demographic history and evolutionary forces that have
shaped populations and drive speciation. Across island systems, contemporary patterns of …

For small and isolated populations, the increased chance of mating between related
individuals can result in a substantial reduction in individual and population fitness. Despite …

The Thoroughbred horse has played an important role in both sporting and economic
aspects of society since the establishment of the breed in the 1700s. The extensive pedigree …