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Recommendations for myeloid-derived suppressor cell nomenclature and characterization standards
Myeloid-derived suppressor cells (MDSCs) have emerged as major regulators of immune
responses in cancer and other pathological conditions. In recent years, ample evidence …
responses in cancer and other pathological conditions. In recent years, ample evidence …
Recent advances in the mechanisms and treatment of immune thrombocytopenia
Primary immune thrombocytopenia is an autoimmune disease associated with a reduced
peripheral blood platelet count. The phenotype is variable with some patients suffering no …
peripheral blood platelet count. The phenotype is variable with some patients suffering no …
Defining the emergence of myeloid-derived suppressor cells in breast cancer using single-cell transcriptomics
Myeloid-derived suppressor cells (MDSCs) are innate immune cells that acquire the
capacity to suppress adaptive immune responses during cancer. It remains elusive how …
capacity to suppress adaptive immune responses during cancer. It remains elusive how …
Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease
M Czech, S Schneider, N Peltokangas… - Science translational …, 2024 - science.org
Acute graft-versus-host disease (aGVHD) is a life-threatening complication of allogeneic
hematopoietic cell transplantation (allo-HCT), for which therapeutic options are limited …
hematopoietic cell transplantation (allo-HCT), for which therapeutic options are limited …
The nature of myeloid-derived suppressor cells in the tumor microenvironment
Myeloid-derived suppressor cells (MDSC) are one of the major components of the tumor
microenvironment. The main feature of these cells is their potent immune suppressive …
microenvironment. The main feature of these cells is their potent immune suppressive …
Coordinated regulation of myeloid cells by tumours
Myeloid cells are the most abundant nucleated haematopoietic cells in the human body and
are a collection of distinct cell populations with many diverse functions. The three groups of …
are a collection of distinct cell populations with many diverse functions. The three groups of …
Myeloid-derived suppressor cells in the tumor microenvironment
M Dysthe, R Parihar - Tumor Microenvironment: Hematopoietic Cells–Part …, 2020 - Springer
Myeloid-derived suppressor cells (MDSCs) represent a heterogenous population of
immature myeloid cells capable of modulating immune responses. In the context of cancer …
immature myeloid cells capable of modulating immune responses. In the context of cancer …
Inhibition of fatty acid oxidation modulates immunosuppressive functions of myeloid-derived suppressor cells and enhances cancer therapies
F Hossain, AA Al-Khami, D Wyczechowska… - Cancer immunology …, 2015 - aacrjournals.org
Myeloid-derived suppressor cells (MDSC) promote tumor growth by inhibiting T-cell
immunity and promoting malignant cell proliferation and migration. The therapeutic potential …
immunity and promoting malignant cell proliferation and migration. The therapeutic potential …
Ablative tumor radiation can change the tumor immune cell microenvironment to induce durable complete remissions
Purpose: The goals of the study were to elucidate the immune mechanisms that contribute to
desirable complete remissions of murine colon tumors treated with single radiation dose of …
desirable complete remissions of murine colon tumors treated with single radiation dose of …
Myeloid-derived suppressor cells: critical cells driving immune suppression in the tumor microenvironment
KH Parker, DW Beury, S Ostrand-Rosenberg - Advances in cancer …, 2015 - Elsevier
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
myeloid cells that suppress innate and adaptive immunity. MDSCs are present in many …
myeloid cells that suppress innate and adaptive immunity. MDSCs are present in many …