Diseases of muscle that are caused by pathological interactions between muscle and the
immune system are devastating, but rare. However, muscle injuries that involve trauma and …

Skeletal muscle regeneration is a complex process orchestrated by multiple steps. Recent
findings indicate that inflammatory responses could play central roles in bridging initial …

Fibroblasts, which are traditionally recognized as a quiescent cell responsible for
extracellular matrix production, are more and more appreciated as an active key player of …

Experimental and clinical data strongly support a role for the eosinophil in the pathogenesis
of asthma, allergic and parasitic diseases, and hypereosinophilic syndromes, in addition to …

Recent discoveries reveal complex interactions between skeletal muscle and the immune
system that regulate muscle regeneration. In this review, we evaluate evidence that …

Skeletal muscle regeneration is highly dependent on the inflammatory response. A wide
variety of innate and adaptive immune cells orchestrate the complex process of muscle …

Fibrosis is the production of excessive amounts of connective tissue, ie, scar formation, in
the course of reactive and reparative processes. Fibrosis develops as a consequence of …

Duchenne muscular dystrophy (DMD) is the most common, lethal, muscle-wasting disease
of childhood. Previous investigations have shown that muscle macrophages may play an …

Discussions of eosinophils are often descriptions of end‐stage effector cells with destructive
capabilities mediated predominantly by released cytotoxic cationic granule proteins …

The immune response to acute muscle damage is important for normal repair. However, in
chronic diseases such as many muscular dystrophies, the immune response can amplify …