Multiscale simulations of biological membranes: the challenge to understand biological phenomena in a living substance
Biological membranes are tricky to investigate. They are complex in terms of molecular
composition and structure, functional over a wide range of time scales, and characterized by …
composition and structure, functional over a wide range of time scales, and characterized by …
Mechanical properties of lipid bilayers from molecular dynamics simulation
Lipid areas (A ℓ), bilayer area compressibilities (KA), bilayer bending constants (KC), and
monolayer spontaneous curvatures (c 0) from simulations using the CHARMM36 force field …
monolayer spontaneous curvatures (c 0) from simulations using the CHARMM36 force field …
Role of the lipid bilayer in outer membrane protein folding in Gram-negative bacteria
β-Barrel outer membrane proteins (OMPs) represent the major proteinaceous component of
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …
the outer membrane (OM) of Gram-negative bacteria. These proteins perform key roles in …
Association between the gut microbiota and diet: Fetal life, early childhood, and further life
Gut microbiota establishment and further microbiota shifts are very important for maintaining
host health throughout life. There are some factors, including genetics, the mother's health …
host health throughout life. There are some factors, including genetics, the mother's health …
Mitochondrial cristae architecture and functions: lessons from minimal model systems
F Joubert, N Puff - Membranes, 2021 - mdpi.com
Mitochondria are known as the powerhouse of eukaryotic cells. Energy production occurs in
specific dynamic membrane invaginations in the inner mitochondrial membrane called …
specific dynamic membrane invaginations in the inner mitochondrial membrane called …
Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission
N Stepanyants, PJ Macdonald, CA Francy… - Molecular biology of …, 2015 - Am Soc Cell Biol
Cardiolipin (CL) is an atypical, dimeric phospholipid essential for mitochondrial dynamics in
eukaryotic cells. Dynamin-related protein 1 (Drp1), a cytosolic member of the dynamin …
eukaryotic cells. Dynamin-related protein 1 (Drp1), a cytosolic member of the dynamin …
[HTML][HTML] Role of charged lipids in membrane structures—Insight given by simulations
S Pöyry, I Vattulainen - Biochimica et Biophysica Acta (BBA)-Biomembranes, 2016 - Elsevier
Lipids and proteins are the main components of cell membranes. It is becoming increasingly
clear that lipids, in addition to providing an environment for proteins to work in, are in many …
clear that lipids, in addition to providing an environment for proteins to work in, are in many …
[HTML][HTML] Atomistic resolution structure and dynamics of lipid bilayers in simulations and experiments
Accurate details on the sampled atomistic resolution structures of lipid bilayers can be
experimentally obtained by measuring C–H bond order parameters, spin relaxation rates …
experimentally obtained by measuring C–H bond order parameters, spin relaxation rates …
Ant1 activation and inhibition patterns support the fatty acid cycling mechanism for proton transport
Adenine nucleotide translocase (ANT) is a well-known mitochondrial exchanger of ATP
against ADP. In contrast, few studies have shown that ANT also mediates proton transport …
against ADP. In contrast, few studies have shown that ANT also mediates proton transport …
Selective interaction of colistin with lipid model membranes
FG Dupuy, I Pagano, K Andenoro, MF Peralta… - Biophysical journal, 2018 - cell.com
Although colistin's clinical use is limited due to its nephrotoxicity, colistin is considered to be
an antibiotic of last resort because it is used to treat patients infected with multidrug-resistant …
an antibiotic of last resort because it is used to treat patients infected with multidrug-resistant …