[HTML][HTML] Secretion of immunoregulatory cytokines by mesenchymal stem cells

D Kyurkchiev, I Bochev… - World journal of stem …, 2014 - ncbi.nlm.nih.gov
According to the minimal criteria of the International Society of Cellular Therapy,
mesenchymal stem cells (MSCs) are a population of undifferentiated cells defined by their …

Mesenchymal stem cell therapy for osteoarthritis: the critical role of the cell secretome

P Mancuso, S Raman, A Glynn, F Barry… - … in bioengineering and …, 2019 - frontiersin.org
Osteoarthritis (OA) is an inflammatory condition still lacking effective treatments.
Mesenchymal stem/stromal cells (MSCs) have been successfully employed in pre-clinical …

Beneficial effects of autologous mesenchymal stem cell transplantation in active progressive multiple sclerosis

P Petrou, I Kassis, N Levin, F Paul, Y Backner… - Brain, 2020 - academic.oup.com
In this study (trial registration: NCT02166021), we aimed to evaluate the optimal way of
administration, the safety and the clinical efficacy of mesenchymal stem cell (MSC) …

Mesenchymal stem cells for the treatment of neurodegenerative disease

N Joyce, G Annett, L Wirthlin, S Olson… - Regenerative …, 2010 - Taylor & Francis
Mesenchymal stem cells/marrow stromal cells (MSCs) present a promising tool for cell
therapy, and are currently being tested in US FDA-approved clinical trials for myocardial …

Bone marrow mesenchymal stem cell transplantation in patients with multiple sclerosis: a pilot study

B Yamout, R Hourani, H Salti, W Barada… - Journal of …, 2010 - Elsevier
We explore the safety, and therapeutic benefit of intrathecal injection of ex-vivo expanded
autologous bone marrow derived mesenchymal stem cells (BM-MSCs) in 10 patients with …

Therapeutic potential of mesenchymal stem cells in regenerative medicine

DM Patel, J Shah, AS Srivastava - Stem cells international, 2013 - Wiley Online Library
Mesenchymal stem cells (MSCs) are stromal cells that have the ability to self‐renew and
also exhibit multilineage differentiation into both mesenchymal and nonmesenchymal …

[HTML][HTML] Neuroprotective effects of intravitreal mesenchymal stem cell transplantation in experimental glaucoma

TV Johnson, ND Bull, DP Hunt, N Marina… - … & visual science, 2010 - arvojournals.org
Purpose.: Retrograde neurotrophic factor transport blockade has been implicated in the
pathophysiology of glaucoma. Stem cell transplantation appears to ameliorate some …

Microglia and neuroprotection: from in vitro studies to therapeutic applications

E Polazzi, B Monti - Progress in neurobiology, 2010 - Elsevier
Microglia are the main immune cells in the brain, playing a role in both physiological and
pathological conditions. Microglial involvement in neurodegenerative diseases is well …

Hypoxia-preconditioned mesenchymal stem cells prevent renal fibrosis and inflammation in ischemia-reperfusion rats

N Ishiuchi, A Nakashima, S Doi, K Yoshida… - Stem cell research & …, 2020 - Springer
Abstract Background Mesenchymal stem cells (MSCs) have been reported to promote the
regeneration of injured tissue via their paracrine abilities, which are enhanced by hypoxic …

[HTML][HTML] Mesenchymal stem cells: Molecular characteristics and clinical applications

F Rastegar, D Shenaq, J Huang, W Zhang… - World journal of stem …, 2010 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) are non-hematopoietic stem cells with the capacity to
differentiate into tissues of both mesenchymal and non-mesenchymal origin. MSCs can …