Biocatalysis: enzymatic synthesis for industrial applications

S Wu, R Snajdrova, JC Moore… - Angewandte Chemie …, 2021 - Wiley Online Library
Biocatalysis has found numerous applications in various fields as an alternative to chemical
catalysis. The use of enzymes in organic synthesis, especially to make chiral compounds for …

Biocatalytic oxidation reactions: a chemist's perspective

JJ Dong, E Fernández‐Fueyo… - Angewandte Chemie …, 2018 - Wiley Online Library
Oxidation chemistry using enzymes is approaching maturity and practical applicability in
organic synthesis. Oxidoreductases (enzymes catalysing redox reactions) enable chemists …

Accessing non-natural reactivity by irradiating nicotinamide-dependent enzymes with light

MA Emmanuel, NR Greenberg, DG Oblinsky, TK Hyster - Nature, 2016 - nature.com
Enzymes are ideal for use in asymmetric catalysis by the chemical industry, because their
chemical compositions can be tailored to a specific substrate and selectivity pattern while …

Recent advances in whole cell biocatalysis techniques bridging from investigative to industrial scale

J Wachtmeister, D Rother - Current opinion in biotechnology, 2016 - Elsevier
Highlights•The use of whole cell biocatalysts is appealing due to their inexpensive
production.•Applications in unconventional media allow high substrate and product …

Alcohol dehydrogenases as catalysts in organic synthesis

AS de Miranda, CDF Milagre, F Hollmann - Frontiers in Catalysis, 2022 - frontiersin.org
Alcohol dehydrogenases (ADHs) have become important catalysts for stereoselective
oxidation and reduction reactions of alcohols, aldehydes and ketones. The aim of this …

[PDF][PDF] How Green is Biocatalysis? To Calculate is To Know.

Y Ni, D Holtmann, F Hollmann - ChemCatChem, 2014 - researchgate.net
Green chemistry aims to minimize the environmental hazards of chemical processes and
their products. Ever since its introduction by Anastas,[1] this principle has inspired …

Alternate heme ligation steers activity and selectivity in engineered cytochrome P450-catalyzed carbene-transfer reactions

K Chen, SQ Zhang, OF Brandenberg… - Journal of the …, 2018 - ACS Publications
We report a biocatalytic platform of engineered cytochrome P450 enzymes to carry out
carbene-transfer reactions using a lactone-based carbene precursor. By simply altering the …

Process intensification as game changer in enzyme catalysis

BO Burek, AWH Dawood, F Hollmann, A Liese… - Frontiers in …, 2022 - frontiersin.org
Enzyme catalysis, made tremendous progress over the last years in identification of new
enzymes and new enzymatic reactivity's as well as optimization of existing enzymes …

A review of the pharmacological activities and recent synthetic advances of γ-butyrolactones

J Hur, J Jang, J Sim - International Journal of Molecular Sciences, 2021 - mdpi.com
γ-Butyrolactone, a five-membered lactone moiety, is one of the privileged structures of
diverse natural products and biologically active small molecules. Because of their broad …

One-pot photoenzymatic synthesis of maleic acid and its derivatives from bio-based furfural via catalytic cascades

SM Zou, JP Wang, MH Zong, ZL Wang, ZJ Zheng… - Green …, 2023 - pubs.rsc.org
Recently, catalytic valorization of biomass-driven furfural has attracted great interest. In this
work, we report a one-pot photoenzymatic route toward maleic acid (MA) and its C4 …