The multiple roles of interferon regulatory factor family in health and disease

L Wang, Y Zhu, N Zhang, Y **an, Y Tang, J Ye… - … and Targeted Therapy, 2024 - nature.com
Abstract Interferon Regulatory Factors (IRFs), a family of transcription factors, profoundly
influence the immune system, impacting both physiological and pathological processes …

Recent advances on high-efficiency of microRNAs in different types of lung cancer: a comprehensive review

MS Sadeghi, M Lotfi, N Soltani, E Farmani… - Cancer cell …, 2023 - Springer
Carcinoma of the lung is among the most common types of cancer globally. Concerning its
histology, it is categorized as a non-small cell carcinoma (NSCLC) and a small cell cancer …

[HTML][HTML] Detection of circulating exosomal miR-17-5p serves as a novel non-invasive diagnostic marker for non-small cell lung cancer patients

Y Zhang, Y Zhang, Y Yin, S Li - Pathology-Research and Practice, 2019 - Elsevier
Exosome-shuttled bioactive miRNAs act as novel non-invasive biomarkers for cancer
diagnosis have received increasing attention. In this study, we aimed to investigate the …

Biology of MiR-17-92 cluster and its progress in lung cancer

X Zhang, Y Li, P Qi, Z Ma - International journal of medical …, 2018 - pmc.ncbi.nlm.nih.gov
MicroRNAs, a class of short endogenous RNAs, acting as post-transcriptional regulators of
gene expression, mostly silence gene expression via binding imperfectly matched …

The dual functional role of MicroRNA-18a (miR-18a) in cancer development

K Shen, Z Cao, R Zhu, L You, T Zhang - Clinical and translational …, 2019 - Springer
Abstract The polycistronic miR-17-92 cluster is instrumental in physiological processes
commonly dysregulated in cancer, such as proliferation, the cell cycle, apoptosis, and …

miR-224-5p-enriched exosomes promote tumorigenesis by directly targeting androgen receptor in non-small cell lung cancer

J Zhou, H Wang, Q Sun, X Liu, Z Wu, X Wang… - … Therapy Nucleic Acids, 2021 - cell.com
Non-small cell lung cancer (NSCLC) is the most common form of cancer, resulting in cancer-
related deaths worldwide. Exosomes, a subclass of extracellular vesicles, are produced and …

The emerging roles of autophagy-related microRNAs in cancer

C Shan, X Chen, H Cai, X Hao, J Li… - … journal of biological …, 2021 - pmc.ncbi.nlm.nih.gov
Autophagy is a conserved catabolic process involving the degradation and recycling of
damaged biomacromolecules or organelles through lysosomal-dependent pathways and …

TCPA v3. 0: an integrative platform to explore the pan-cancer analysis of functional proteomic data

MJM Chen, J Li, Y Wang, R Akbani, Y Lu… - Molecular & Cellular …, 2019 - mcponline.org
Reverse-phase protein arrays represent a powerful functional proteomics approach to
characterizing cell signaling pathways and understanding their effects on cancer …

Enhanced inhibition of tumorigenesis using combinations of miRNA-targeted therapeutics

S Miroshnichenko, O Patutina - Frontiers in pharmacology, 2019 - frontiersin.org
The search for effective strategies to inhibit tumorigenesis remains one of the most relevant
scientific challenges. Among the most promising approaches is the direct modulation of the …

Autophagy-related MicroRNAs in chronic lung diseases and lung cancer

S Rezaei, M Mahjoubin-Tehran… - Critical reviews in …, 2020 - Elsevier
Chronic lung disease has become a leading cause of death in recent years. Despite several
attempts to discover and develop new therapeutic approaches, patients often suffer a poor …