The vertebrate vasculature forms an extensive branched network of blood vessels that
supplies tissues with nutrients and oxygen. During vascular development, coordinated …

Morphogenesis is the remarkable process by which cells self-assemble into complex tissues
and organs that exhibit specialized form and function during embryological development …

The zebrafish (Danio rerio) is increasingly being used to study basic vertebrate biology and
human disease with a rich array of in vivo genetic and molecular tools. However, the inability …

Multicellular aggregates of circulating tumor cells (CTC clusters) are potent initiators of
distant organ metastasis. However, it is currently assumed that CTC clusters are too large to …

Endothelial cells (ECs) line the inside of blood vessels and respond to mechanical cues
generated by blood flow. Mechanical stimuli regulate the localization of YAP by reorganizing …

The correct development of blood vessels is crucial for all aspects of tissue growth and
physiology in vertebrates. The formation of an elaborate hierarchically branched network of …

Cadherins are transmembrane proteins that mediate cell–cell adhesion in animals. By
regulating contact formation and stability, cadherins play a crucial role in tissue …

Vascular networks are formed and maintained through a multitude of angiogenic processes,
such as sprouting, anastomosis and pruning. Only recently has it become possible to study …

Background & Aims Non-alcoholic fatty liver disease/non-alcoholic steatohepatitis
(NAFLD/NASH) is an increasing clinical problem associated with progression to …