The reconceptualization of Alzheimer's disease (AD) as a clinical and biological construct
has facilitated the development of biomarker-guided, pathway-based targeted therapies …

Although there is no unanimity, growing evidence supports the value of regular physical
exercise to prevent Alzheimer's disease as well as cognitive decline in affected patients …

Neuroinflammation commences decades before Alzheimer's disease (AD) clinical onset and
represents one of the earliest pathomechanistic alterations throughout the AD continuum …

Alzheimer's disease (AD) is characterized by non-linear, genetic-driven pathophysiological
dynamics with high heterogeneity in biological alterations and disease spatial-temporal …

The evidence of a connection between the peripheral inflammatory processes and
neurodegenerative diseases of the central nervous system is becoming more apparent. This …

Decades of experimental and clinical research have contributed to unraveling many
mechanisms in the pathogenesis of Alzheimer's disease (AD), but the puzzle is still …

Noninvasive brain stimulation techniques (NiBS) have gathered substantial interest in the
study of dementia, considered their possible role in help defining diagnostic biomarkers of …

Alzheimer's disease (AD) is a multifactorial, age-related neurological disease characterized
by complex pathophysiological dynamics taking place at multiple biological levels, including …

Individual variations in drug efficacy, side effects and adverse drug reactions are still
challenging that cannot be ignored in drug research and development. The aim of …

Alzheimer disease (AD) is a neurodegenerative disorder characterized pathologically by the
presence of neurofibrillary tangles and amyloid beta (Aβ) plaques in the brain. The disease …