Polymeric nanoparticles for drug delivery

MA Beach, U Nayanathara, Y Gao, C Zhang… - Chemical …, 2024 - ACS Publications
The recent emergence of nanomedicine has revolutionized the therapeutic landscape and
necessitated the creation of more sophisticated drug delivery systems. Polymeric …

Nanotechnology's frontier in combatting infectious and inflammatory diseases: prevention and treatment

Y Huang, X Guo, Y Wu, X Chen, L Feng, N **e… - … and Targeted Therapy, 2024 - nature.com
Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

Vaccine adjuvants: mechanisms and platforms

T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …

[HTML][HTML] Nanoparticle-based delivery systems for vaccines

R Bezbaruah, VP Chavda, L Nongrang, S Alom… - Vaccines, 2022 - mdpi.com
Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional
vaccinations may have low immunogenicity and, in most situations, only provide partial …

Nanoparticle vaccines against infectious diseases

R Pati, M Shevtsov, A Sonawane - Frontiers in immunology, 2018 - frontiersin.org
Due to emergence of new variants of pathogenic micro-organisms the treatment and
immunization of infectious diseases have become a great challenge in the past few years. In …

Biomaterial-assisted biotherapy: A brief review of biomaterials used in drug delivery, vaccine development, gene therapy, and stem cell therapy

X Han, A Alu, H Liu, Y Shi, X Wei, L Cai, Y Wei - Bioactive materials, 2022 - Elsevier
Biotherapy has recently become a hotspot research topic with encouraging prospects in
various fields due to a wide range of treatments applications, as demonstrated in preclinical …

The mRNA vaccine revolution: COVID-19 has launched the future of vaccinology

Z Ye, J Harmon, W Ni, Y Li, D Wich, Q Xu - ACS nano, 2023 - ACS Publications
During the COVID-19 pandemic, mRNA (mRNA) vaccines emerged as leading vaccine
candidates in a record time. Nonreplicating mRNA (NRM) and self-amplifying mRNA (SAM) …

[HTML][HTML] Nanoparticle vaccines

L Zhao, A Seth, N Wibowo, CX Zhao, N Mitter, C Yu… - Vaccine, 2014 - Elsevier
Nanotechnology increasingly plays a significant role in vaccine development. As vaccine
development orientates toward less immunogenic “minimalist” compositions, formulations …

PLGA-based nanoparticles: an overview of biomedical applications

F Danhier, E Ansorena, JM Silva, R Coco… - Journal of controlled …, 2012 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …

Adjuvants: Classification, Modus Operandi, and Licensing

JS Apostolico, VAS Lunardelli… - Journal of …, 2016 - Wiley Online Library
Vaccination is one of the most efficient strategies for the prevention of infectious diseases.
Although safer, subunit vaccines are poorly immunogenic and for this reason the use of …