On modeling

DS Novikov, VG Kiselev… - Magnetic resonance in …, 2018 - Wiley Online Library
Map** tissue microstructure with MRI holds great promise as a noninvasive window into
tissue organization at the cellular level. Having originated within the realm of diffusion NMR …

Imaging brain microstructure with diffusion MRI: practicality and applications

DC Alexander, TB Dyrby, M Nilsson… - NMR in …, 2019 - Wiley Online Library
This article gives an overview of microstructure imaging of the brain with diffusion MRI and
reviews the state of the art. The microstructure‐imaging paradigm aims to estimate and map …

[HTML][HTML] SANDI: A compartment-based model for non-invasive apparent soma and neurite imaging by diffusion MRI

M Palombo, A Ianus, M Guerreri, D Nunes… - Neuroimage, 2020 - Elsevier
This work introduces a compartment-based model for apparent cell body (namely soma) and
neurite density imaging (SANDI) using non-invasive diffusion-weighted MRI (DW-MRI). The …

[HTML][HTML] Investigating white matter fibre density and morphology using fixel-based analysis

DA Raffelt, JD Tournier, RE Smith, DN Vaughan… - Neuroimage, 2017 - Elsevier
Voxel-based analysis of diffusion MRI data is increasingly popular. However, most white
matter voxels contain contributions from multiple fibre populations (often referred to as …

Quantifying brain microstructure with diffusion MRI: Theory and parameter estimation

DS Novikov, E Fieremans, SN Jespersen… - NMR in …, 2019 - Wiley Online Library
We review, systematize and discuss models of diffusion in neuronal tissue, by putting them
into an overarching physical context of coarse‐graining over an increasing diffusion length …

Ageing and brain white matter structure in 3,513 UK Biobank participants

SR Cox, SJ Ritchie, EM Tucker-Drob… - Nature …, 2016 - nature.com
Quantifying the microstructural properties of the human brain's connections is necessary for
understanding normal ageing and disease. Here we examine brain white matter magnetic …

[HTML][HTML] Neurite Exchange Imaging (NEXI): A minimal model of diffusion in gray matter with inter-compartment water exchange

IO Jelescu, A de Skowronski, F Geffroy, M Palombo… - NeuroImage, 2022 - Elsevier
Biophysical models of diffusion in white matter have been center-stage over the past two
decades and are essentially based on what is now commonly referred to as the “Standard …

[HTML][HTML] Multi-compartment microscopic diffusion imaging

E Kaden, ND Kelm, RP Carson, MD Does… - NeuroImage, 2016 - Elsevier
This paper introduces a multi-compartment model for microscopic diffusion anisotropy
imaging. The aim is to estimate microscopic features specific to the intra-and extra-neurite …

[HTML][HTML] Can MRI measure myelin? Systematic review, qualitative assessment, and meta-analysis of studies validating microstructural imaging with myelin histology

A Lazari, I Lipp - Neuroimage, 2021 - Elsevier
Recent years have seen an increased understanding of the importance of myelination in
healthy brain function and neuropsychiatric diseases. Non-invasive microstructural magnetic …

NODDI: practical in vivo neurite orientation dispersion and density imaging of the human brain

H Zhang, T Schneider, CA Wheeler-Kingshott… - Neuroimage, 2012 - Elsevier
This paper introduces neurite orientation dispersion and density imaging (NODDI), a
practical diffusion MRI technique for estimating the microstructural complexity of dendrites …