Role of the gut microbiota and its metabolites in tumorigenesis or development of colorectal cancer

R Qu, Y Zhang, Y Ma, X Zhou, L Sun, C Jiang… - Advanced …, 2023‏ - Wiley Online Library
Colorectal cancer (CRC) is the most common cancer of the digestive system with high
mortality and morbidity rates. Gut microbiota is found in the intestines, especially the …

The transition from genomics to phenomics in personalized population health

JT Yurkovich, SJ Evans, N Rappaport, JL Boore… - Nature Reviews …, 2024‏ - nature.com
Modern health care faces several serious challenges, including an ageing population and
its inherent burden of chronic diseases, rising costs and marginal quality metrics. By …

[HTML][HTML] Perspective: leveraging the gut microbiota to predict personalized responses to dietary, prebiotic, and probiotic interventions

SM Gibbons, T Gurry, JW Lampe, A Chakrabarti… - Advances in …, 2022‏ - Elsevier
Humans often show variable responses to dietary, prebiotic, and probiotic interventions.
Emerging evidence indicates that the gut microbiota is a key determinant for this population …

Rethinking the classification of non‐digestible carbohydrates: Perspectives from the gut microbiome

S Fan, Z Zhang, Q Nie, M Ackah… - … Reviews in Food …, 2024‏ - Wiley Online Library
Clarification is required when the term “carbohydrate” is used interchangeably with
“saccharide” and “glycan.” Carbohydrate classification based on human digestive enzyme …

Exploring gut microbial metabolites as key players in inhibition of cancer progression: mechanisms and therapeutic implications

T Yin, X Zhang, Y **ong, B Li, D Guo, Z Sha, X Lin… - Microbiological …, 2024‏ - Elsevier
The gut microbiota plays a critical role in numerous biochemical processes essential for
human health, such as metabolic regulation and immune system modulation. An increasing …

Unlocking the therapeutic potential of Huoxiang Zhengqi San in cold and high humidity-induced diarrhea: Insights into intestinal microbiota modulation and digestive …

Y Wu, N Deng, J Liu, Y Cai, X Yi, Z Tan - Heliyon, 2024‏ - cell.com
Abstract Huoxiang Zhengqi San (HXZQS), a traditional Chinese herbal formula, enjoys
widespread use in Chinese medicine to treat diarrhea with cold-dampness trapped spleen …

Healthy aging and the human gut microbiome: why we cannot just turn back the clock

T Wilmanski, SM Gibbons, ND Price - Nature aging, 2022‏ - nature.com
The aging research field has largely focused on reversing aging-related changes in the
body. However, emerging evidence about the gut microbiome indicates that it may not be …

[HTML][HTML] Effects of an amino acid-based formula supplemented with two human milk oligosaccharides on growth, tolerability, safety, and gut microbiome in infants with …

MS Gold, PJ Quinn, DE Campbell, J Peake, J Smart… - Nutrients, 2022‏ - mdpi.com
This open-label, non-randomized, multicenter trial (Registration: NCT 03661736) aimed to
assess if an amino acid-based formula (AAF) supplemented with two human milk …

Uterine microbial communities and their potential role in the regulation of epithelium cell cycle and apoptosis in aged hens

D Dai, J Wang, H Zhang, S Wu, G Qi - Microbiome, 2023‏ - Springer
Background Alterations of the uterine microbiome are closely associated with various
intrauterine diseases and physiological conditions, which are well-established in mammals …

[HTML][HTML] Microbial and Metabolic Gut Profiling across Seven Malignancies Identifies Fecal Faecalibacillus intestinalis and Formic Acid as Commonly Altered in Cancer …

M Kulecka, P Czarnowski, A Bałabas, M Turkot… - International Journal of …, 2024‏ - mdpi.com
The key association between gut dysbiosis and cancer is already known. Here, we used
whole-genome shotgun sequencing (WGS) and gas chromatography/mass spectrometry …