Toll‐like receptors (TLRs): structure, functions, signaling, and role of their polymorphisms in colorectal cancer susceptibility

AS Sameer, S Nissar - BioMed Research International, 2021 - Wiley Online Library
Toll‐like receptors (TLRs) are the important mediators of inflammatory pathways in the gut
which play a major role in mediating the immune responses towards a wide variety of …

Toll-like receptors in immunity and inflammatory diseases: Past, present, and future

K Vijay - International immunopharmacology, 2018 - Elsevier
The immune system is a very diverse system of the host that evolved during evolution to
cope with various pathogens present in the vicinity of environmental surroundings inhabited …

Pattern-recognition receptors in endometriosis: A narrative review

B Guo, J Chen, J Zhang, Y Fang, X Liu… - Frontiers in …, 2023 - frontiersin.org
Endometriosis is closely associated with ectopic focal inflammation and immunosuppressive
microenvironment. Multiple types of pattern recognition receptors (PRRs) are present in the …

Bacteria-activated macrophage membrane coated ROS-responsive nanoparticle for targeted delivery of antibiotics to infected wounds

Y Luo, X Jia, X Wu, L Diao, Y Zhao, X Liu… - Journal of …, 2024 - Springer
Bacterial infections and antibiotic resistance represent significant global public health
challenges, necessitating the development of innovative antibacterial agents with targeted …

TLR3 agonists: RGC100, ARNAX, and poly-IC: A comparative review

A Komal, M Noreen, AF El-Kott - Immunologic Research, 2021 - Springer
Abstract Toll-like receptors 3 (TLR3) have been broadly studied among all TLRs over the
last few decades together with its agonists due to their contribution to cancer regression …

Toll‐like receptors: The role in bladder cancer development, progression and immunotherapy

S Ohadian Moghadam… - Scandinavian journal of …, 2019 - Wiley Online Library
Bladder cancer is one of the leading causes of death worldwide. The main immune
mechanisms which lead to bladder cancer development or treatment outcomes have yet to …

Investigation of TLR2 and TLR4 polymorphisms and sepsis susceptibility: computational and experimental approaches

MY Behairy, AA Abdelrahman, EA Toraih… - International journal of …, 2022 - mdpi.com
Toll-like receptors (TLR) play an eminent role in the regulation of immune responses to
invading pathogens during sepsis. TLR genetic variants might influence individual …

Role of toll-like receptors and th responses in viral myocarditis

SY Zheng, JZ Dong - Frontiers in immunology, 2022 - frontiersin.org
Myocarditis is the common cause of sudden cardiac death, dilated cardiomyopathy (DCM)
and heart failure (HF) in young adults. The most common type of myocarditis is viral …

[HTML][HTML] Therapeutic potential of plant-derived natural compounds in Alzheimer's disease: Targeting microglia-mediated neuroinflammation

Y Shen, F Liu, M Zhang - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Microglia are resident immune cells of the central nervous system (CNS) with roles in
sensing, housekee**, and defense. Exploring the role of microglia in the occurrence and …

Toll-like receptors in cardiac hypertrophy

Y Zhang, J Wu, E Dong, Z Wang, H **ao - Frontiers in Cardiovascular …, 2023 - frontiersin.org
Toll-like receptors (TLRs) are a family of pattern recognition receptors (PRRs) that can
identify pathogen-associated molecular patterns (PAMPs) and damage-associated …