Epigenetic alterations pose one major hallmark of organismal aging. Here, we provide an
overview on recent findings describing the epigenetic changes that arise during aging and …

Caloric restriction extends healthy lifespan in multiple species. Intermittent fasting, an
alternative form of dietary restriction, is potentially more sustainable in humans, but its …

Spinal cord injury (SCI) causes lifelong debilitating conditions. Previous works demonstrated
the essential role of the immune system in recovery after SCI. Here, we explored the …

Aging is the slowest process in a living organism. During this process, mortality rate
increases exponentially due to the accumulation of damage at the cellular level. Cellular …

Frailty indexes (FIs) provide quantitative measurements of nonspecific health decline and
are particularly useful as longitudinal monitors of morbidity in aging studies. For mouse …

Caloric restriction (CR) delays aging and extends healthy lifespan in multiple species.
Alternative forms of dietary restriction (DR) such as intermittent fasting (IF) have drawn …

Aging involves a transition from youthful vigor to geriatric infirmity and death. Individuals who
remain vigorous longer tend to live longer, and within isogenic populations of C. elegan s …

In aging, physiologic networks decline in function at rates that differ between individuals,
producing a wide distribution of lifespan. Though 70% of human lifespan variance remains …

Ageing is an inherent and intricate biological process that takes place in living organisms as
time progresses. It involves the decline of multiple physiological functions, leading to body …

Aging is the single largest risk factor for most chronic diseases, and thus possesses large
socioeconomic interest to continuously aging societies. Consequently, the field of aging …