Solid-state nanochannels for bio-marker analysis

Y Huang, L Liu, C Luo, W Liu, X Lou, L Jiang… - Chemical Society …, 2023 - pubs.rsc.org
Bio-markers, such as ions, small molecules, nucleic acids, peptides, proteins and cells,
participate in the construction of living organisms and play important roles in biological …

Solid-state nanopore sensors

L Xue, H Yamazaki, R Ren, M Wanunu… - Nature Reviews …, 2020 - nature.com
Nanopore-based sensors have established themselves as a prominent tool for solution-
based, single-molecule analysis of the key building blocks of life, including nucleic acids …

Advances in biosensors and diagnostic technologies using nanostructures and nanomaterials

EC Welch, JM Powell, TB Clevinger… - Advanced Functional …, 2021 - Wiley Online Library
Nanoscale materials have unique properties that make them especially useful for
biomedical diagnostic applications. Recent developments in nanoengineering have resulted …

The application of single molecule nanopore sensing for quantitative analysis

Y Wu, JJ Gooding - Chemical Society Reviews, 2022 - pubs.rsc.org
Nanopore-based sensors typically work by monitoring transient pulses in conductance via
current–time traces as molecules translocate through the nanopore. The unique property of …

Fabrication of angstrom-scale two-dimensional channels for mass transport

A Bhardwaj, MV Surmani Martins, Y You, R Sajja… - Nature protocols, 2024 - nature.com
Fluidic channels at atomic scales regulate cellular trafficking and molecular filtration across
membranes, and thus play crucial roles in the functioning of living systems. However …

[HTML][HTML] Recent progress of biomarker detection sensors

R Liu, X Ye, T Cui - Research, 2020 - spj.science.org
Early cancer diagnosis and treatment are crucial research fields of human health. One
method that has proven efficient is biomarker detection which can provide real-time and …

Nanopore-based strategy for selective detection of single carcinoembryonic antigen (CEA) molecules

H Tang, H Wang, C Yang, D Zhao, Y Qian… - Analytical …, 2020 - ACS Publications
Nanopores have become one of the most important tools for single-molecule sensing, but
the challenge for selective detection of specific biomolecules still exists. In this contribution …

Glass capillary-based nanopores for single molecule/single cell detection

X Guan, H Li, L Chen, G Qi, Y ** - ACS sensors, 2023 - ACS Publications
A glass capillary-based nanopore (G-nanopore), due to its tapered tip, easy tunability in
orifice size, and especially its flexible surface modifications that can be tailored to effectively …

Identification of Conformational Variants for Bradykinin Biomarker Peptides from a Biofluid Using a Nanopore and Machine Learning

SJ Greive, L Bacri, B Cressiot, J Pelta - ACS nano, 2023 - ACS Publications
There is a current need to develop methods for the sensitive detection of peptide biomarkers
in complex mixtures of molecules, such as biofluids, to enable early disease detection …

Multiplex quantitative detection of SARS-CoV-2 specific IgG and IgM antibodies based on DNA-assisted nanopore sensing

Z Zhang, X Wang, X Wei, SW Zheng, BJ Lenhart… - Biosensors and …, 2021 - Elsevier
Abstract The coronavirus disease (COVID-19) caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has spread into a global pandemic. Early and accurate …