Force fields for protein simulations

JW Ponder, DA Case - Advances in protein chemistry, 2003 - Elsevier
Publisher Summary The chapter focuses on a general description of the force fields that are
most commonly used at present, and it gives an indication of the directions of current …

Empirical force fields for biological macromolecules: overview and issues

AD MacKerell Jr - Journal of computational chemistry, 2004 - Wiley Online Library
Empirical force field‐based studies of biological macromolecules are becoming a common
tool for investigating their structure–activity relationships at an atomic level of detail. Such …

AMBER, a package of computer programs for applying molecular mechanics, normal mode analysis, molecular dynamics and free energy calculations to simulate the …

DA Pearlman, DA Case, JW Caldwell, WS Ross… - Computer Physics …, 1995 - Elsevier
We describe the development, current features, and some directions for future development
of the AMBER package of computer programs. This package has evolved from a program …

[BOOK][B] The theory of intermolecular forces

A Stone - 2013 - books.google.com
The theory of intermolecular forces has advanced very greatly in recent years. It has become
possible to carry out accurate calculations of intermolecular forces for molecules of useful …

A five-site model for liquid water and the reproduction of the density anomaly by rigid, nonpolarizable potential functions

MW Mahoney, WL Jorgensen - The Journal of chemical physics, 2000 - pubs.aip.org
The ability of simple potential functions to reproduce accurately the density of liquid water
from− 37 to 100° C at 1 to 10 000 atm has been further explored. The result is the five-site …

Polarizable atomic multipole water model for molecular mechanics simulation

P Ren, JW Ponder - The Journal of Physical Chemistry B, 2003 - ACS Publications
A new classical empirical potential is proposed for water. The model uses a polarizable
atomic multipole description of electrostatic interactions. Multipoles through the quadrupole …

Dynamical fluctuating charge force fields: Application to liquid water

SW Rick, SJ Stuart, BJ Berne - The Journal of chemical physics, 1994 - pubs.aip.org
A new molecular dynamics model in which the point charges on atomic sites are allowed to
fluctuate in response to the environment is developed and applied to water. The idea for …

QM/MM: what have we learned, where are we, and where do we go from here?

H Lin, DG Truhlar - Theoretical Chemistry Accounts, 2007 - Springer
This paper briefly reviews the current status of the most popular methods for combined
quantum mechanical/molecular mechanical (QM/MM) calculations, including their …

How water's properties are encoded in its molecular structure and energies

E Brini, CJ Fennell, M Fernandez-Serra… - Chemical …, 2017 - ACS Publications
How are water's material properties encoded within the structure of the water molecule? This
is pertinent to understanding Earth's living systems, its materials, its geochemistry and …

Polarizable atomic multipole-based AMOEBA force field for proteins

Y Shi, Z **a, J Zhang, R Best, C Wu… - Journal of chemical …, 2013 - ACS Publications
Development of the AMOEBA (atomic multipole optimized energetics for biomolecular
simulation) force field for proteins is presented. The current version (AMOEBA-2013) utilizes …