Cholinergic modulation of the hippocampal region and memory function

J Haam, JL Yakel - Journal of neurochemistry, 2017 - Wiley Online Library
Acetylcholine (AC h) plays an important role in memory function and has been implicated in
aging‐related dementia, in which the impairment of hippocampus‐dependent learning …

Expression and function of the cholinergic system in immune cells

T Fujii, M Mashimo, Y Moriwaki, H Misawa… - Frontiers in …, 2017 - frontiersin.org
T and B cells express most cholinergic system components—eg, acetylcholine (ACh),
choline acetyltransferase (ChAT), acetylcholinesterase, and both muscarinic and nicotinic …

[HTML][HTML] Nicotinic acetylcholine receptors: Therapeutic targets for novel ligands to treat pain and inflammation

AJ Hone, JM McIntosh - Pharmacological research, 2023 - Elsevier
Nicotinic acetylcholine receptors (nAChRs) have been historically defined as ligand-gated
ion channels and function as such in the central and peripheral nervous systems. Recently …

Neurobiological mechanisms of nicotine reward and aversion

L Wills, JL Ables, KM Braunscheidel… - Pharmacological …, 2022 - Elsevier
Neuronal nicotinic acetylcholine receptors (nAChRs) regulate the rewarding actions of
nicotine contained in tobacco that establish and maintain the smoking habit. nAChRs also …

Neuronal and extraneuronal nicotinic acetylcholine receptors

M Zoli, S Pucci, A Vilella, C Gotti - Current neuropharmacology, 2018 - ingentaconnect.com
Neuronal nicotinic acetylcholine receptors (nAChRs) belong to a super-family of Cysloop
ligand-gated ion channels that respond to endogenous acetylcholine (ACh) or other …

Nicotinic acetylcholine receptors: from basic science to therapeutics

R Hurst, H Rollema, D Bertrand - Pharmacology & therapeutics, 2013 - Elsevier
Substantial progress in the identification of genes encoding for a large number of proteins
responsible for various aspects of neurotransmitter release, postsynaptic detection and …

Neonicotinoids: insecticides acting on insect nicotinic acetylcholine receptors

K Matsuda, SD Buckingham, D Kleier, JJ Rauh… - Trends in …, 2001 - cell.com
Imidacloprid is increasingly used worldwide as an insecticide. It is an agonist at nicotinic
acetylcholine receptors (nAChRs) and shows selective toxicity for insects over vertebrates …

Neuronal nicotinic receptors: from structure to pathology

C Gotti, F Clementi - Progress in neurobiology, 2004 - Elsevier
Neuronal nicotinic receptors (NAChRs) form a heterogeneous family of ion channels that are
differently expressed in many regions of the central nervous system (CNS) and peripheral …

[HTML][HTML] Structural mechanisms of α7 nicotinic receptor allosteric modulation and activation

SM Burke, M Avstrikova, CM Noviello, N Mukhtasimova… - Cell, 2024 - cell.com
The α7 nicotinic acetylcholine receptor is a pentameric ligand-gated ion channel that plays
an important role in cholinergic signaling throughout the nervous system. Its unique …

Emerging molecular mechanisms of signal transduction in pentameric ligand-gated ion channels

Á Nemecz, MS Prevost, A Menny, PJ Corringer - Neuron, 2016 - cell.com
Nicotinic acetylcholine, serotonin type 3, γ-amminobutyric acid type A, and glycine receptors
are major players of human neuronal communication. They belong to the family of …