Molecular probes, chemosensors, and nanosensors for optical detection of biorelevant molecules and ions in aqueous media and biofluids

J Krämer, R Kang, LM Grimm, L De Cola… - Chemical …, 2022 - ACS Publications
Synthetic molecular probes, chemosensors, and nanosensors used in combination with
innovative assay protocols hold great potential for the development of robust, low-cost, and …

Aggregation-Induced Emission Luminogen: Role in Biopsy for Precision Medicine

Y Duo, L Han, Y Yang, Z Wang, L Wang… - Chemical …, 2024 - ACS Publications
Biopsy, including tissue and liquid biopsy, offers comprehensive and real-time physiological
and pathological information for disease detection, diagnosis, and monitoring. Fluorescent …

Metabolomics for laboratory diagnostics

R Bujak, W Struck-Lewicka, MJ Markuszewski… - … of pharmaceutical and …, 2015 - Elsevier
Metabolomics is an emerging approach in a systems biology field. Due to continuous
development in advanced analytical techniques and in bioinformatics, metabolomics has …

Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and …

UV Mahajan, VR Varma, ME Griswold… - PLoS …, 2020 - journals.plos.org
Background There is growing evidence that Alzheimer disease (AD) is a pervasive
metabolic disorder with dysregulation in multiple biochemical pathways underlying its …

The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum, and plasma compartments

AF Almulla, A Vasupanrajit, C Tunvirachaisakul… - Molecular …, 2022 - nature.com
The tryptophan catabolite (TRYCAT) pathway is implicated in the pathophysiology of
schizophrenia (SCZ) since the rate-limiting enzyme indoleamine-dioxygenase (IDO) may be …

Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction

F Guan, T Ni, W Zhu, LK Williams, LB Cui, M Li… - Molecular …, 2022 - nature.com
Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritability and
complex inheritance. In the past decade, successful identification of numerous susceptibility …

A systematic review of metabolite biomarkers of schizophrenia

J Davison, A O'Gorman, L Brennan, DR Cotter - Schizophrenia research, 2018 - Elsevier
Current diagnosis of schizophrenia relies exclusively on the potentially subjective
interpretation of clinical symptoms and social functioning as more objective biological …

Twenty years of amino acid determination using capillary electrophoresis: A review

HY Ta, F Collin, L Perquis, V Poinsot, V Ong-Meang… - Analytica chimica …, 2021 - Elsevier
In this review, we have attempted to highlight the advancements in the the field of 17 amino
acid determination using capillary electrophoresis. The technique has been developed 18 …

Dysregulation of kynurenine pathway and potential dynamic changes of kynurenine in schizophrenia: A systematic review and meta-analysis

B Cao, Y Chen, Z Ren, Z Pan, RS McIntyre… - … & Biobehavioral Reviews, 2021 - Elsevier
The kynurenine (KYN) pathway is postulated to play various roles in immune system
dysregulation of schizophrenia (SCZ). We conducted a meta-analysis to explore the …

Plasma metabolites predict severity of depression and suicidal ideation in psychiatric patients-a multicenter pilot analysis

D Setoyama, TA Kato, R Hashimoto, H Kunugi… - PloS one, 2016 - journals.plos.org
Evaluating the severity of depression (SOD), especially suicidal ideation (SI), is crucial in the
treatment of not only patients with mood disorders but also psychiatric patients in general …