Chemical and pharmacological aspects of caffeic acid and its activity in hepatocarcinoma

KMM Espíndola, RG Ferreira, LEM Narvaez… - Frontiers in …, 2019 - frontiersin.org
Caffeic acid (CA) is a phenolic compound synthesized by all plant species and is present in
foods such as coffee, wine, tea, and popular medicines such as propolis. This phenolic acid …

Milk thistle (Silybum marianum): A concise overview on its chemistry, pharmacological, and nutraceutical uses in liver diseases

L Abenavoli, AA Izzo, N Milić, C Cicala… - Phytotherapy …, 2018 - Wiley Online Library
Milk thistle (MT; Silybum marianum), a member of the Asteraceae family, is a therapeutic
herb with a 2,000‐year history of use. MT fruits contain a mixture of flavonolignans …

Hepatocellular Carcinoma (HCC) in Egypt: A comprehensive overview

WM Rashed, MAM Kandeil, MO Mahmoud… - Journal of the Egyptian …, 2020 - Springer
Background Worldwide, hepatocellular carcinoma (HCC) is a universal problem and its
epidemiological data showed variation from place to place. Hepatocellular carcinoma (HCC) …

Molecular signaling pathways and therapeutic targets in hepatocellular carcinoma

M Dimri, A Satyanarayana - Cancers, 2020 - mdpi.com
Hepatocellular carcinoma (HCC) is a complex biological process and is often diagnosed at
advanced stages with no effective treatment options. With advances in tumor biology and …

[PDF][PDF] Hepatocellular carcinoma in 2021: an exhaustive update

CA Philips, S Rajesh, DC Nair, R Ahamed… - Cureus, 2021 - cureus.com
Primary liver cancer is a challenging global health concern with an estimated more than a
million persons to be affected annually by the year 2025. The commonest type is …

[HTML][HTML] Current status of sorafenib nanoparticle delivery systems in the treatment of hepatocellular carcinoma

FH Kong, QF Ye, XY Miao, X Liu, SQ Huang, L **ong… - Theranostics, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common type of liver cancer and one of the
leading causes of cancer-related death worldwide. Advanced HCC displays strong …

[HTML][HTML] Synergetic delivery of triptolide and Ce6 with light-activatable liposomes for efficient hepatocellular carcinoma therapy

L Yu, Z Wang, Z Mo, B Zou, Y Yang, R Sun… - … Pharmaceutica Sinica B, 2021 - Elsevier
Hepatocellular carcinoma (HCC) has been known as the second common leading cancer
worldwide, as it responds poorly to both chemotherapy and medication. Triptolide (TP), a …

[HTML][HTML] Mechanisms of hepatocellular carcinoma progression

OO Ogunwobi, T Harricharran, J Huaman… - World journal of …, 2019 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the most common primary malignancy of the liver. It is
the second leading cause of cancer-related deaths worldwide, with a very poor prognosis. In …

The evolving role of immune checkpoint inhibitors in hepatocellular carcinoma treatment

P Leone, AG Solimando, R Fasano, A Argentiero… - Vaccines, 2021 - mdpi.com
Hepatocellular carcinoma (HCC) is one of most common cancers and the fourth leading
cause of death worldwide. Commonly, HCC development occurs in a liver that is severely …

The exosome encapsulated microRNAs as circulating diagnostic marker for hepatocellular carcinoma with low alpha‐fetoprotein

S Ghosh, S Bhowmik, S Majumdar… - … journal of cancer, 2020 - Wiley Online Library
Diagnosis of hepatocellular carcinoma (HCC) remains challenging to clinicians, particularly
in a patient with low alpha‐fetoprotein. Here, in silico, ex vivo and in vitro data were …