Nuclear receptors (NRs) are a family of transcription factors that regulate numerous
physiological processes such as metabolism, reproduction, inflammation, as well as the …

Omega-3 polyunsaturated fatty acids (PUFAs) exhibit neuroprotective properties and
represent a potential treatment for a variety of neurodegenerative and neurological …

This chapter presents an overview of the current status of studies on the structural and
molecular biology of the retinoid X receptor subtypes α, β, and γ (RXRs, NR2B1–3), their …

Per-and polyfluoroalkyl substances (PFAS) are a broad class of hundreds of fluorinated
chemicals with environmental health concerns due to their widespread presence and …

The physiological effects of retinoic acids (RAs) are mediated by members of two families of
nuclear receptors, the retinoic acid receptors (RARs) and the retinoid X receptors (RXRs) …

Nuclear receptors (NRs) constitute a large and highly conserved family of ligand-activated
transcription factors that regulate diverse biological processes such as development …

The molting process in arthropods is regulated by steroid hormones acting via nuclear
receptor proteins. The most common molting hormone is the ecdysteroid, 20 …

The nuclear receptor heterodimers of liver X receptor (LXR) and retinoid X receptor (RXR)
are key transcriptional regulators of genes involved in lipid homeostasis and inflammation …

Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are members of the nuclear
receptor superfamily whose effects on cell growth and survival can be modulated …

1.1. Retinoid Path to Nuclear Receptors Retinol, the lipid-soluble vitamin A, is an absolute
requirement for normal growth, vision, and differentiation of epithelial tissues in mammals. 1 …