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Biochemical and mechanical regulation of actin dynamics
Polymerization of actin filaments against membranes produces force for numerous cellular
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …
processes, such as migration, morphogenesis, endocytosis, phagocytosis and organelle …
Effects of extracellular matrix viscoelasticity on cellular behaviour
Substantial research over the past two decades has established that extracellular matrix
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …
(ECM) elasticity, or stiffness, affects fundamental cellular processes, including spreading …
Viscoelastic cell microenvironment: hydrogel‐based strategy for recapitulating dynamic ECM mechanics
Y Ma, T Han, Q Yang, J Wang, B Feng… - Advanced Functional …, 2021 - Wiley Online Library
The native extracellular matrix (ECM) generally exhibits dynamic mechanical properties and
displays time‐dependent responses to deformation or mechanical loading, in terms of …
displays time‐dependent responses to deformation or mechanical loading, in terms of …
Actin dynamics, architecture, and mechanics in cell motility
Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …
drives a large range of cellular processes including polarity establishment, morphogenesis …
Viscoelastic hydrogels for 3D cell culture
O Chaudhuri - Biomaterials science, 2017 - pubs.rsc.org
In tissues, many cells are surrounded by and interact with a three-dimensional soft
extracellular matrix (ECM). Both the physical and biochemical properties of the ECM play a …
extracellular matrix (ECM). Both the physical and biochemical properties of the ECM play a …
Modeling semiflexible polymer networks
This is an overview of theoretical approaches to semiflexible polymers and their networks.
Such semiflexible polymers have large bending rigidities that can compete with the entropic …
Such semiflexible polymers have large bending rigidities that can compete with the entropic …
Strain-enhanced stress relaxation impacts nonlinear elasticity in collagen gels
The extracellular matrix (ECM) is a complex assembly of structural proteins that provides
physical support and biochemical signaling to cells in tissues. The mechanical properties of …
physical support and biochemical signaling to cells in tissues. The mechanical properties of …
Cell mechanics and the cytoskeleton
The ability of a eukaryotic cell to resist deformation, to transport intracellular cargo and to
change shape during movement depends on the cytoskeleton, an interconnected network of …
change shape during movement depends on the cytoskeleton, an interconnected network of …
Investigating cell mechanics with atomic force microscopy
Transmission of mechanical force is crucial for normal cell development and functioning.
However, the process of mechanotransduction cannot be studied in isolation from cell …
However, the process of mechanotransduction cannot be studied in isolation from cell …
Dynamic molecular processes mediate cellular mechanotransduction
Cellular responses to mechanical forces are crucial in embryonic development and adult
physiology, and are involved in numerous diseases, including atherosclerosis …
physiology, and are involved in numerous diseases, including atherosclerosis …