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The role of cancer-associated fibroblasts and fibrosis in liver cancer
Liver cancer is the second leading cause of cancer mortality worldwide, causing more than
700,000 deaths annually. Because of the wide landscape of genomic alterations and limited …
700,000 deaths annually. Because of the wide landscape of genomic alterations and limited …
Mechanism and its regulation of tumor-induced angiogenesis
Tumor angiogenesis is the proliferation of a network of blood vessels that penetrates into
cancerous growths, supplying nutrients and oxygen and removing waste products. The …
cancerous growths, supplying nutrients and oxygen and removing waste products. The …
Bioglass activated skin tissue engineering constructs for wound healing
Wound healing is a complicated process, and fibroblast is a major cell type that participates
in the process. Recent studies have shown that bioglass (BG) can stimulate fibroblasts to …
in the process. Recent studies have shown that bioglass (BG) can stimulate fibroblasts to …
FGF/FGFR-dependent molecular mechanisms underlying anti-cancer drug resistance
Simple Summary Deregulation of the FGF/FGFR axis is associated with many types of
cancer and contributes to the development of chemoresistance, limiting the effectiveness of …
cancer and contributes to the development of chemoresistance, limiting the effectiveness of …
Vascular endothelial growth factor and receptor interaction is a prerequisite for murine hepatic fibrogenesis
H Yoshiji, S Kuriyama, J Yoshii, Y Ikenaka, R Noguchi… - Gut, 2003 - gut.bmj.com
Background: It has been shown that expression of the potent angiogenic factor, vascular
endothelial growth factor (VEGF), and its receptors, flt-1 (VEGFR-1) and KDR/Flk-1 (VEGFR …
endothelial growth factor (VEGF), and its receptors, flt-1 (VEGFR-1) and KDR/Flk-1 (VEGFR …
The genetic and epigenetic alterations in human hepatocellular carcinoma: a recent update
Hepatocellular carcinoma (HCC) is one of the most frequent human malignancies worldwide
with very poor prognosis. It is generally accepted that the progression of HCC is a long-term …
with very poor prognosis. It is generally accepted that the progression of HCC is a long-term …
[HTML][HTML] Antagonist antibodies to vascular endothelial growth factor receptor 2 (VEGFR-2) as anti-angiogenic agents
Interaction of numerous signaling pathways in endothelial and mesangial cells results in
exquisite control of the process of physiological angiogenesis, with a central role played by …
exquisite control of the process of physiological angiogenesis, with a central role played by …
In-situ forming hydrogel based on thiolated chitosan/carboxymethyl cellulose (CMC) containing borate bioactive glass for wound healing
Suitable wound dressings for accelerating wound healing are actively being designed and
synthesised. In this study, thiolated chitosan (tCh)/oxidized carboxymethyl cellulose (OCMC) …
synthesised. In this study, thiolated chitosan (tCh)/oxidized carboxymethyl cellulose (OCMC) …
Bioglass promotes wound healing by affecting gap junction connexin 43 mediated endothelial cell behavior
It is well known that gap junctions play an important role in wound healing, and bioactive
glass (BG) has been shown to help healing when applied as a wound dressing. However …
glass (BG) has been shown to help healing when applied as a wound dressing. However …
[HTML][HTML] Cancer gene discovery in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a deadly cancer, whose incidence is increasing
worldwide. Albeit the main risk factors for HCC development have been clearly identified …
worldwide. Albeit the main risk factors for HCC development have been clearly identified …