Causal machine learning for healthcare and precision medicine

P Sanchez, JP Voisey, T **a… - Royal Society …, 2022 - royalsocietypublishing.org
Causal machine learning (CML) has experienced increasing popularity in healthcare.
Beyond the inherent capabilities of adding domain knowledge into learning systems, CML …

Artificial intelligence for quantitative modeling in drug discovery and development: An innovation and quality consortium perspective on use cases and best practices

N Terranova, D Renard, MH Shahin… - Clinical …, 2024 - Wiley Online Library
Recent breakthroughs in artificial intelligence (AI) and machine learning (ML) have ushered
in a new era of possibilities across various scientific domains. One area where these …

Nonparametric estimation of heterogeneous treatment effects: From theory to learning algorithms

A Curth, M Van der Schaar - International Conference on …, 2021 - proceedings.mlr.press
The need to evaluate treatment effectiveness is ubiquitous in most of empirical science, and
interest in flexibly investigating effect heterogeneity is growing rapidly. To do so, a multitude …

Explainable AI for glaucoma prediction analysis to understand risk factors in treatment planning

MS Kamal, N Dey, L Chowdhury… - IEEE Transactions …, 2022 - ieeexplore.ieee.org
Glaucoma causes irreversible blindness. In 2020, about 80 million people worldwide had
glaucoma. Existing machine learning (ML) models are limited to glaucoma prediction, where …

Diffused responsibility: attributions of responsibility in the use of AI-driven clinical decision support systems

H Bleher, M Braun - AI and Ethics, 2022 - Springer
Good decision-making is a complex endeavor, and particularly so in a health context. The
possibilities for day-to-day clinical practice opened up by AI-driven clinical decision support …

Transfer learning on heterogeneous feature spaces for treatment effects estimation

I Bica, M van der Schaar - Advances in Neural Information …, 2022 - proceedings.neurips.cc
Consider the problem of improving the estimation of conditional average treatment effects
(CATE) for a target domain of interest by leveraging related information from a source …

Continuous-time modeling of counterfactual outcomes using neural controlled differential equations

N Seedat, F Imrie, A Bellot, Z Qian… - arxiv preprint arxiv …, 2022 - arxiv.org
Estimating counterfactual outcomes over time has the potential to unlock personalized
healthcare by assisting decision-makers to answer''what-iF''questions. Existing causal …

Estimating the effects of continuous-valued interventions using generative adversarial networks

I Bica, J Jordon… - Advances in Neural …, 2020 - proceedings.neurips.cc
While much attention has been given to the problem of estimating the effect of discrete
interventions from observational data, relatively little work has been done in the setting of …

Really doing great at estimating CATE? a critical look at ML benchmarking practices in treatment effect estimation

A Curth, D Svensson, J Weatherall… - Thirty-fifth conference …, 2021 - openreview.net
The machine learning (ML) toolbox for estimation of heterogeneous treatment effects from
observational data is expanding rapidly, yet many of its algorithms have been evaluated …

In search of insights, not magic bullets: Towards demystification of the model selection dilemma in heterogeneous treatment effect estimation

A Curth, M Van Der Schaar - International Conference on …, 2023 - proceedings.mlr.press
Personalized treatment effect estimates are often of interest in high-stakes applications–
thus, before deploying a model estimating such effects in practice, one needs to be sure that …