Autophagy and cancer drug resistance in dialogue: pre-clinical and clinical evidence
The emergence of drug resistance is a major challenge for oncologists. Resistance can be
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
categorized as acquired or intrinsic; the alteration of several biological mechanisms …
Ferroptosis as a potential target for cancer therapy
Ferroptosis is a recently discovered essential type of cell death that is mainly characterized
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …
by iron overload and lipid peroxidation. Emerging evidence suggests that ferroptosis is a …
An injectable and active hydrogel induces mutually enhanced mild magnetic hyperthermia and ferroptosis
X Chen, H Wang, J Shi, Z Chen, Y Wang, S Gu, Y Fu… - Biomaterials, 2023 - Elsevier
Magnetic hyperthermia therapy (MHT) is a promising new modality to deal with solid tumors,
yet the low magnetic-heat conversion efficacy, magnetic resonance imaging (MRI) artifacts …
yet the low magnetic-heat conversion efficacy, magnetic resonance imaging (MRI) artifacts …
Autophagy-dependent ferroptosis in cancer
Significance: Autophagy is a self-degrading process that determines cell fate in response to
various environmental stresses. In contrast to autophagy-mediated cell survival, the signals …
various environmental stresses. In contrast to autophagy-mediated cell survival, the signals …
In situ hydrogel based on Cu–Fe3O4 nanoclusters exploits oxidative stress and the ferroptosis/cuproptosis pathway for chemodynamic therapy
Y Zhang, N Zhang, J **ng, Y Sun, X **, C Shen… - Biomaterials, 2024 - Elsevier
Chemodynamic therapy (CDT) involving the use of metal nanozymes presents new
opportunities for the treatment of deep-seated tumors. However, the lower ROS catalytic rate …
opportunities for the treatment of deep-seated tumors. However, the lower ROS catalytic rate …
Recent advances in cancer therapeutic copper-based nanomaterials for antitumor therapy
R Aishajiang, Z Liu, T Wang, L Zhou, D Yu - Molecules, 2023 - mdpi.com
Copper serves as a vital microelement which is widely present in the biosystem, functioning
as multi-enzyme active site, including oxidative stress, lipid oxidation and energy …
as multi-enzyme active site, including oxidative stress, lipid oxidation and energy …
NIR responsive composite nanomaterials with in-situ deposition of cascaded nanozymes for multiple synergistic therapy of bacterial infection in diabetic mice
Y Zhang, C Wen, Y Liu, A Li, Q Guo, X Zhang… - Chemical Engineering …, 2023 - Elsevier
The bacterial infection of chronic wounds caused by diabetes has imposed a significant
burden on society and families. Therefore, the collaborative and emerging antibacterial …
burden on society and families. Therefore, the collaborative and emerging antibacterial …
International consensus guidelines for the definition, detection, and interpretation of autophagy-dependent ferroptosis
Macroautophagy/autophagy is a complex degradation process with a dual role in cell death
that is influenced by the cell types that are involved and the stressors they are exposed to …
that is influenced by the cell types that are involved and the stressors they are exposed to …
Ultrasound activatable microneedles for bilaterally augmented sono-chemodynamic and sonothermal antibacterial therapy
M Liang, L Shang, Y Yu, Y Jiang, Q Bai, J Ma, D Yang… - Acta Biomaterialia, 2023 - Elsevier
Chemodynamic therapy (CDT) employs Fenton catalysts to kill bacteria by converting
hydrogen peroxide (H 2 O 2) into toxic hydroxyl radical (• OH). Among them, Fenton-type …
hydrogen peroxide (H 2 O 2) into toxic hydroxyl radical (• OH). Among them, Fenton-type …
Exploration of Ultrasound‐Sensitive Biomaterials in Cancer Theranostics
Cancer is a serious health problem to be solved. With the development of biomaterials,
enhanced diagnostic and controllable therapeutic strategies for cancer have emerged …
enhanced diagnostic and controllable therapeutic strategies for cancer have emerged …