Pyroptosis is a proinflammatory form of programmed cell death featured with membrane
pore formation that causes cellular swelling and allows the release of intracellular …

Necrotizing soft tissue infections (NSTIs) are critical clinical conditions characterized by
extensive necrosis of any layer of the soft tissue and systemic toxicity. Group A streptococci …

Streptococcus pyogenes is a human-specific pathogen that commonly colonizes the upper
respiratory tract and skin, causing a wide variety of diseases ranging from pharyngitis to …

Group A Streptococcus (GAS, Streptococcus pyogenes) is a Gram-positive human pathogen
that employs several secreted and surface-bound virulence factors to manipulate its …

Group A Streptococcus (GAS, Streptococcus pyogenes) is a professional human pathogen
that commonly infects the skin. Keratinocytes are one of the first cells to contact GAS, and by …

Abstract Group A Streptococcus (GAS) is a Gram‐positive bacterial pathogen that causes an
array of infectious diseases in humans. Accumulating clinical evidence suggests that …

Abstract Group A Streptococcus (GAS) is a Gram‐positive bacterial pathogen that causes
significant morbidity and mortality worldwide. Recent clinical evidence suggests that the …

Group B Streptococcus (GBS) is an opportunistic pathogen that causes preterm birth and
neonatal disease. Although GBS is known to exhibit vast diversity in virulence across strains …

The genus Streptococcus infects a broad range of hosts, including humans. Some species,
such as S. pyogenes, S. agalactiae, S. pneumoniae, and S. mutans, are recognized as the …

Streptococcus pyogenes strains produce a wide variety of secreted or released extracellular
products, many of which are virulence factors due to their roles in promoting disease and/or …