Fluorescence resonance energy transfer at the single-molecule level

T Ha, J Fei, S Schmid, NK Lee… - Nature Reviews …, 2024 - nature.com
Fluorescence resonance energy transfer (FRET) is a powerful spectroscopic method for
measuring distances in the 2–8 nm range. Often, conformational changes and molecular …

Single-molecule FRET for probing nanoscale biomolecular dynamics

D Nettels, N Galvanetto, MT Ivanović, M Nüesch… - Nature Reviews …, 2024 - nature.com
Single-molecule spectroscopy is a powerful method for studying the physics of molecular
systems, particularly biomolecules, such as proteins and nucleic acids. By avoiding …

Artificial intelligence-driven quantification of antibiotic-resistant Bacteria in food by color-encoded multiplex hydrogel digital LAMP

T Yang, X Zhang, Y Yan, Y Liu, X Lin, W Li - Food Chemistry, 2025 - Elsevier
Antibiotic-resistant bacteria pose considerable risks to global health, particularly through
transmission in the food chain. Herein, we developed the artificial intelligence-driven …

Probing actin‐activated ATP turnover kinetics of human cardiac myosin II by single molecule fluorescence

A Berg, LP Velayuthan, S Tågerud, M Ušaj… - …, 2024 - Wiley Online Library
Mechanistic insights into myosin II energy transduction in striated muscle in health and
disease would benefit from functional studies of a wide range of point‐mutants. This …

An evaluation of recent advancements in biological sensory organ-inspired neuromorphically tuned biomimetic devices

A Sinha, J Lee, J Kim, H So - Materials Horizons, 2024 - pubs.rsc.org
In the field of neuroscience, significant progress has been made regarding how the brain
processes information. Unlike computer processors, the brain comprises neurons and …

Programming morphological and mechanical performance of cyclic ori-kirigami via design-feasible parameter space

R He, Y Chen, J Shi, Y Bai, J Feng - Thin-Walled Structures, 2025 - Elsevier
Recent advances in origami and kirigami have enabled the creation of unconventional
structures that utilize precise folding and strategic cutting to achieve complex functionalities …

Deep learning based local feature classification to automatically identify single molecule fluorescence events

S Zhou, Y Miao, H Qiu, Y Yao, W Wang… - Communications …, 2024 - nature.com
Long-term single-molecule fluorescence measurements are widely used powerful tools to
study the conformational dynamics of biomolecules in real time to further elucidate their …

Artificial Intelligence‐Enhanced Analysis of Genomic DNA Visualized with Nanoparticle‐Tagged Peptides under Electron Microscopy

PR Sundharbaabu, J Chang, Y Kim, Y Shim, B Lee… - Small, 2024 - Wiley Online Library
DNA visualization has advanced across multiple microscopy platforms, albeit with limited
progress in the identification of novel staining agents for electron microscopy (EM) …

Pretrained Deep Neural Network Kin-SiM for Single-Molecule FRET Trace Idealization

L Zhang, J Li, NG Walter - The Journal of Physical Chemistry B, 2025 - ACS Publications
Single-molecule fluorescence resonance energy transfer (smFRET) has emerged as a
pivotal technique for probing biomolecular dynamics over time at nanometer scales …

Deep-LASI, single-molecule data analysis software

P Asadiatouei, CB Salem, S Wanninger, E Ploetz… - Biophysical …, 2024 - cell.com
By avoiding ensemble averaging, single-molecule methods provide novel means of
extracting mechanistic insights into function of material and molecules at the nanoscale …