Progress in the field of prosthetic cardiovascular devices has significantly contributed to the
rapid advancements in cardiac therapy during the last four decades. The concept of …

Ventricular assist devices (VADs) provide long-and short-term support to chronically ill heart
disease patients; these devices are expected to match the remarkable functionality of the …

Computational fluid dynamics (CFD) is increasingly being used to develop blood-contacting
medical devices. However, the lack of standardized methods for validating CFD simulations …

While computational fluid dynamics (CFD) is commonly used for medical device
development, its usefulness for demonstrating device safety has not been proven. Reliable …

Experimental and computational studies were performed to elucidate the role of turbulent
stresses in mechanical blood damage (hemolysis). A suspension of bovine red blood cells …

Patient-specific simulation plays an important role in cardiovascular disease research,
diagnosis, surgical planning and medical device design, as well as education in …

We investigate the influence of the fluid constitutive model on the outcome of shape
optimization tasks, motivated by optimal design problems in biomedical engineering. Our …

Background Extracorporeal carbon dioxide removal (ECCO 2 R) uses an extracorporeal
circuit to directly remove carbon dioxide from the blood either in lieu of mechanical …

This study is part of a FDA-sponsored project to evaluate the use and limitations of
computational fluid dynamics (CFD) in assessing blood flow parameters related to medical …

Predictive simulation and optimization-based design tools have great potential to improve
the design of surgeries and interventions used in cardiovascular medicine. The present work …