Lipid metabolic reprogramming is an emerging hallmark of cancer. In order to sustain
uncontrolled proliferation and survive in unfavorable environments that lack oxygen and …

Glioblastoma (GBM) is the most lethal primary brain tumor. With limited therapeutic options,
novel therapies are desperately needed. Recent studies have shown that GBM acquires …

A lipid droplet (LD) is an organelle that consists of a phospholipid monolayer and a neutral
lipid core, with proteins embedded in or attached to its surface. Until recently, cancers had …

Currently, cancer treatment mainly consists of surgery, radiotherapy, chemotherapy,
immunotherapy, and molecular targeted therapy, of which radiotherapy is one of the major …

Radiotherapy resistance is a major obstacle to nasopharyngeal carcinoma (NPC) therapy
and contributes to tumour recurrence and metastasis. Lipid metabolism is a key regulatory …

Glioblastoma is the most common form of primary malignant brain tumor in adults and one of
the most lethal human cancers, with high recurrence and therapy resistance. Glioblastoma …

Elevated lipid metabolism is one of hallmarks of malignant tumors. Lipids not only serve as
essential structural components of biological membranes but also provide energy and …

Simple Summary Cancer cells are characterized by an increased energy metabolism, to
cope with a high rate of proliferation. Recently, alterations in lipid metabolism have been …

Lipid metabolism is widely reprogrammed in tumor cells. Lipid droplet is a common
organelle existing in most mammal cells, and its complex and dynamic functions in …

Ferroptosis is a kind of oxidative stress-dependent cell death characterized by iron
accumulation and lipid peroxidation. It can work in conjunction with radiation to increase …