miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay–a review
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
efforts have been exerted to improve BC patients' care. Besides, new approaches have …
Molecular biology of bladder cancer: new insights into pathogenesis and clinical diversity
MA Knowles, CD Hurst - Nature reviews cancer, 2015 - nature.com
Urothelial carcinoma of the bladder comprises two long-recognized disease entities with
distinct molecular features and clinical outcome. Low-grade non-muscle-invasive tumours …
distinct molecular features and clinical outcome. Low-grade non-muscle-invasive tumours …
The miR-200 family of microRNAs: fine tuners of epithelial-mesenchymal transition and circulating cancer biomarkers
Simple Summary MicroRNAs (miRNAs) are small RNA molecules that regulate gene
expression by blocking translation or inducing degradation of specific gene transcripts. The …
expression by blocking translation or inducing degradation of specific gene transcripts. The …
PRMT5 circular RNA promotes metastasis of urothelial carcinoma of the bladder through sponging miR-30c to induce epithelial–mesenchymal transition
Abstract Purpose: Circular RNAs (circRNAs), a novel class of noncoding RNAs, have
recently drawn lots of attention in the pathogenesis of human cancers. However, the role of …
recently drawn lots of attention in the pathogenesis of human cancers. However, the role of …
MicroRNA and cancer–a brief overview
MicroRNAs (miRNAs) are short non-coding RNAs with a length of∼ 22 nucleotides,
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …
involved in posttranscriptional regulation of gene expression. Until now, over 2588 miRNAs …
ZEB1: at the crossroads of epithelial-mesenchymal transition, metastasis and therapy resistance
Zinc finger E-box binding homeobox 1 (ZEB1) is a transcription factor that promotes tumor
invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) in carcinoma …
invasion and metastasis by inducing epithelial-mesenchymal transition (EMT) in carcinoma …
Understanding the effectiveness of natural compound mixtures in cancer through their molecular mode of action
Many approaches to cancer management are often ineffective due to adverse reactions,
drug resistance, or inadequate target specificity of single anti-cancer agents. In contrast, a …
drug resistance, or inadequate target specificity of single anti-cancer agents. In contrast, a …
The basics of epithelial–mesenchymal transition (EMT): A study from a structure, dynamics, and functional perspective
Epithelial–mesenchymal transition (EMT) is a key step in transdifferentiation process in solid
cancer development. Forthcoming evidence suggest that the stratified program transforms …
cancer development. Forthcoming evidence suggest that the stratified program transforms …
MicroRNAs in human cancer
Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20–23-nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …
length that control gene expression in many cellular processes. These molecules typically …
MicroRNAs in development and disease
MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …
introduced an additional level of intricacy to our understanding of gene regulation. There are …