Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease

F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …

Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis

M Schrag, C Mueller, M Zabel, A Crofton… - Neurobiology of …, 2013 - Elsevier
Abnormal oxidative stress is an established feature of Alzheimer's disease, but clinical trials
aiming to reduce oxidative stress have not yet proven an effective therapy for dementia …

Alterations of plasma magnesium, copper, zinc, iron and selenium concentrations and some related erythrocyte antioxidant enzyme activities in patients with …

H Vural, H Demirin, Y Kara, I Eren, N Delibas - Journal of Trace Elements in …, 2010 - Elsevier
The aim of the present study is to evaluate the status of plasma essential trace elements
magnesium (Mg), copper (Cu), zinc (Zn), iron (Fe) and selenium (Se) concentrations and …

[HTML][HTML] Cerium oxide based nanozymes: Redox phenomenon at biointerfaces

S Singh - Biointerphases, 2016 - pubs.aip.org
Cerium oxide nanoparticles (nanoceria) are known to exhibit enzymelike activity, such as
biological catalase, oxidase, superoxide dismutase, and peroxidase enzymelike activities …

Late-onset Alzheimer's disease is associated with inherent changes in bioenergetics profiles

KC Sonntag, WI Ryu, KM Amirault, RA Healy… - Scientific reports, 2017 - nature.com
Body-wide changes in bioenergetics, ie, energy metabolism, occur in normal aging and
disturbed bioenergetics may be an important contributing mechanism underlying late-onset …

Delineation of neuroprotective effects and possible benefits of antioxidantstherapy for the treatment of Alzheimer's diseases by targeting mitochondrial-derived …

V Walia, D Kaushik, V Mittal, K Kumar, R Verma… - Molecular …, 2021 - Springer
Alzheimer's disease (AD) is considered the sixth leading cause of death in elderly patients
and is characterized by progressive neuronal degeneration and impairment in memory …

Oxidative stress and metabolic syndrome: cause or consequence of Alzheimer′ s disease?

D Luque-Contreras, K Carvajal… - Oxidative medicine …, 2014 - Wiley Online Library
Alzheimer's disease (AD) is a major neurodegenerative disease affecting the elderly.
Clinically, it is characterized by a progressive loss of memory and cognitive function …

The roles of biomarkers of oxidative stress and antioxidant in Alzheimer's disease: a systematic review

YT Chang, WN Chang, NW Tsai… - BioMed research …, 2014 - Wiley Online Library
Purpose. Oxidative stress plays an important role in the pathogenesis of Alzheimer's disease
(AD). This paper aims to examine whether biomarkers of oxidative stress and antioxidants …

Reduced hippocampal volume in healthy young ApoE4 carriers: an MRI study

L O'Dwyer, F Lamberton, S Matura, C Tanner… - PloS one, 2012 - journals.plos.org
The E4 allele of the ApoE gene has consistently been shown to be related to an increased
risk of Alzheimer's disease (AD). The E4 allele is also associated with functional and …

Selenium and Alzheimer's disease: a systematic review

M Loef, GN Schrauzer… - Journal of Alzheimer's …, 2011 - content.iospress.com
Preventing Alzheimer's disease (AD) would require knowledge about its etiology to a degree
of detail not yet available. The major hurdle in understanding the disease lies in teasing out …