Protocadherins (Pcdhs) are cell adhesion molecules that belong to the cadherin
superfamily, and are subdivided into clustered (cPcdhs) and non-clustered Pcdhs (ncPcdhs) …

Cadherins are Ca 2+-dependent cell-cell adhesion molecules that play critical roles in
animal morphogenesis. Various cadherin-related molecules have also been identified …

Dendritic arborizations of many neurons are patterned by a process called self-avoidance, in
which branches arising from a single neuron repel each other,,,,,,. By minimizing gaps and …

The chemoaffinity hypothesis for neural circuit assembly posits that axons and their targets
bear matching molecular labels that endow neurons with unique identities and specify …

The neocortex consists of a vast number of diverse neurons that form distinct layers and
intricate circuits at the single-cell resolution to support complex brain functions. Diverse cell …

Astrocytes, which are homeostatic cells of the central nervous system (CNS), display
remarkable heterogeneity in their morphology and function. Besides their physical and …

The specificity of interactions between neurons is believed to be mediated by diverse cell
adhesion molecules, including members of the cadherin superfamily. Whereas mechanisms …

DNA methylation plays key roles in diverse biological processes such as X chromosome
inactivation, transposable element repression, genomic imprinting, and tissue-specific gene …

Neural progenitor cell (NPC) transplantation has high therapeutic potential in neurological
disorders. Functional restoration may depend on the formation of reciprocal connections …

The majority of vertebrate protocadherin (Pcdh) genes are clustered in a single genomic
locus, and this remarkable genomic organization is highly conserved from teleosts to …