[HTML][HTML] Heat shock proteins: agents of cancer development and therapeutic targets in anti-cancer therapy

CW Yun, HJ Kim, JH Lim, SH Lee - Cells, 2019 - mdpi.com
Heat shock proteins (HSPs) constitute a large family of molecular chaperones classified by
their molecular weights, and they include HSP27, HSP40, HSP60, HSP70, and HSP90 …

Constructing a cell microenvironment with biomaterial scaffolds for stem cell therapy

X Zhao, Q Li, Z Guo, Z Li - Stem cell research & therapy, 2021 - Springer
Stem cell therapy is widely recognized as a promising strategy for exerting therapeutic
effects after injury in degenerative diseases. However, limitations such as low cell retention …

Enhanced therapeutic effects of mesenchymal stem cell-derived exosomes with an injectable hydrogel for hindlimb ischemia treatment

K Zhang, X Zhao, X Chen, Y Wei, W Du… - … applied materials & …, 2018 - ACS Publications
Mesenchymal stem cell (MSC)-derived exosomes have been recognized as new candidates
for cell-free treatment of various diseases. However, maintaining the retention and stability of …

Supramolecular nanofibers containing arginine-glycine-aspartate (RGD) peptides boost therapeutic efficacy of extracellular vesicles in kidney repair

C Zhang, Y Shang, X Chen, AC Midgley, Z Wang… - ACS …, 2020 - ACS Publications
Extracellular vesicles (EVs) derived from mesenchymal stem cells (MSC-EVs) have been
recognized as a promising cell-free therapy for acute kidney injury (AKI), which avoids safety …

In Vivo Tracking of Mesenchymal Stem Cell-Derived Extracellular Vesicles Improving Mitochondrial Function in Renal Ischemia–Reperfusion Injury

H Cao, Y Cheng, H Gao, J Zhuang, W Zhang, Q Bian… - ACS …, 2020 - ACS Publications
Extracellular vesicles (EVs) released by mesenchymal stem cells (MSCs) have exhibited
regenerative capability in animal models of ischemia–reperfusion (I/R) acute kidney injury …

Renal endothelial cell‐targeted extracellular vesicles protect the kidney from ischemic injury

K Zhang, R Li, X Chen, H Yan, H Li, X Zhao… - Advanced …, 2023 - Wiley Online Library
Endothelial cell injury plays a critical part in ischemic acute kidney injury (AKI) and
participates in the progression of AKI. Targeting renal endothelial cell therapy may …

Enhanced proangiogenic potential of mesenchymal stem cell-derived exosomes stimulated by a nitric oxide releasing polymer

W Du, K Zhang, S Zhang, R Wang, Y Nie, H Tao, Z Han… - Biomaterials, 2017 - Elsevier
Mesenchymal stem cell (MSC)-derived exosomes have been recognized as new candidates
for the treatment of degenerative diseases or injury and may provide an alternative to cell …

Prostaglandin E2 hydrogel improves cutaneous wound healing via M2 macrophages polarization

S Zhang, Y Liu, X Zhang, D Zhu, X Qi, X Cao… - …, 2018 - pmc.ncbi.nlm.nih.gov
Wound healing is regulated by a complex series of events and overlap** phases. A
delicate balance of cytokines and mediators in tissue repair is required for optimal therapy in …

IGF-1C hydrogel improves the therapeutic effects of MSCs on colitis in mice through PGE2-mediated M2 macrophage polarization

X Cao, L Duan, H Hou, Y Liu, S Chen, S Zhang… - …, 2020 - pmc.ncbi.nlm.nih.gov
Background: Mesenchymal stem cell (MSC)-based therapies hold great promise for the
treatment of inflammatory bowel disease (IBD). In order to optimize and maximize the …

Potential and therapeutic efficacy of cell-based therapy using mesenchymal stem cells for acute/chronic kidney disease

CW Yun, SH Lee - International journal of molecular sciences, 2019 - mdpi.com
Kidney disease can be either acute kidney injury (AKI) or chronic kidney disease (CKD) and
it can lead to the development of functional organ failure. Mesenchymal stem cells (MSCs) …