Allergy: Mechanistic insights into new methods of prevention and therapy

CA Akdis, M Akdis, SD Boyd, V Sampath… - Science Translational …, 2023‏ - science.org
In the past few decades, the prevalence of allergic diseases has increased worldwide. Here,
we review the etiology and pathophysiology of allergic diseases, including the role of the …

[HTML][HTML] Feast for thought: A comprehensive review of food allergy 2021-2023

I Bartha, N Almulhem, AF Santos - Journal of Allergy and Clinical …, 2024‏ - Elsevier
A review of the latest publications in food allergy over the past couple of years confirmed that
food allergy is a major public health concern, affecting about 8% of children and 10% of …

Food allergy, mechanisms, diagnosis and treatment: innovation through a multi‐targeted approach

SB Sindher, A Long, AR Chin, A Hy, V Sampath… - Allergy, 2022‏ - Wiley Online Library
The incidence of food allergy (FA) has continued to rise over the last several decades,
posing significant burdens on health and quality of life. Significant strides into the …

[HTML][HTML] The role of gut microbiota and leaky gut in the pathogenesis of food allergy

R Poto, W Fusco, E Rinninella, M Cintoni, F Kaitsas… - Nutrients, 2023‏ - mdpi.com
Food allergy (FA) is a growing public health concern, with an increasing prevalence in
Western countries. Increasing evidence suggests that the balance of human gut microbiota …

Oral immunotherapy for food allergy: translation from studies to clinical practice?

G Pouessel, G Lezmi - World Allergy Organization Journal, 2023‏ - Elsevier
Oral immunotherapy (OIT) is now recognized as an alternative active treatment to strict food
avoidance in certain patients with IgE-mediated food allergy. Studies have confirmed the …

Evaluation of clinical outcomes of efficacy in food allergen immunotherapy trials, COFAITH EAACI task force

P Rodríguez del Río, M Álvaro‐Lozano, S Arasi… - Allergy, 2024‏ - Wiley Online Library
Food allergy is a global public health problem that until recent years lacked any aetiological
treatment supported by academy, industry and regulators. Food immunotherapy (AIT) is an …

Targeting type 2 immunity and the future of food allergy treatment

MC Berin - Journal of Experimental Medicine, 2023‏ - rupress.org
IgE-mediated food allergy affects 6–8% of the population in the United States. Type 2
immune responses are central to the pathogenesis of food allergy, but type 2 CD4+ T cell …

Varying approaches to management of IgE-mediated food allergy in children around the world

M Lloyd, P Loke, DP Mack, SH Sicherer… - The Journal of Allergy …, 2023‏ - Elsevier
Food allergy is a chronic disease that affects individuals of all ages and is a significant
public health problem globally. This narrative overview examines clinical management …

[HTML][HTML] Boosting vaccine effectiveness: The groundbreaking role of probiotics

M Abavisani, N Ebadpour, A Khoshrou… - Journal of Agriculture and …, 2024‏ - Elsevier
Probiotics, the health-promoting members of the gut microbiota, have been shown to
enhance mucosal and systemic immunity, stimulate cytokines, chemokines, and antibodies …

An update on recent developments and highlights in food allergy

A Locke, L Hung, JEM Upton, L O'Mahony, J Hoang… - Allergy, 2023‏ - Wiley Online Library
While both the incidence and general awareness of food allergies is increasing, the variety
and clinical availability of therapeutics remain limited. Therefore, investigations into the …