Chronic pain exerts an enormous personal and economic burden, affecting more than 30%
of people worldwide according to some studies. Unlike acute pain, which carries survival …

Nociplastic pain is the semantic term suggested by the international community of pain
researchers to describe a third category of pain that is mechanistically distinct from …

This guideline provides recommendations for clinicians providing pain care, including those
prescribing opioids, for outpatients aged≥ 18 years. It updates the CDC Guideline for …

Fibromyalgia is characterized by chronic widespread pain, fatigue, sleep disturbances and
functional symptoms. The etiopathogenesis, diagnostic criteria and classification criteria of …

Fibromyalgia is a syndrome characterized by chronic and widespread musculoskeletal pain,
often accompanied by other symptoms, such as fatigue, intestinal disorders and alterations …

Importance Harms and benefits of opioids for chronic noncancer pain remain unclear.
Objective To systematically review randomized clinical trials (RCTs) of opioids for chronic …

Fibromyalgia syndrome (FMS) is characterized by widespread pain and tenderness, and
patients typically experience fatigue and emotional distress. The etiology and …

The COVID-19 pandemic has impacted the lives and health of persons worldwide, with
potential for further effects in the future. The experience of living within this pandemic has …

Objective To develop evidence-based European Alliance of Associations for Rheumatology
(EULAR) points to consider (PtCs) for the management of difficult-to-treat rheumatoid …

線維筋痛症は, 広範にわたる筋骨格系の慢性的な疼痛と, それに伴う疲労, 睡眠障害,
その他の認知・身体症状を特徴とする疾患である. 多くの患者にとって, これらの症状は何年も続き …