Diabetic peripheral neuropathy: advances in diagnosis and strategies for screening and early intervention

D Selvarajah, D Kar, K Khunti, MJ Davies… - The lancet Diabetes & …, 2019 - thelancet.com
Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 and 2
diabetes. It is a leading cause of lower-limb amputation and disabling neuropathic pain …

Diabetic neuropathy: a position statement by the American Diabetes Association

R Pop-Busui, AJM Boulton, EL Feldman, V Bril… - Diabetes …, 2016 - pmc.ncbi.nlm.nih.gov
Diabetic neuropathies are the most prevalent chronic complications of diabetes. This
heterogeneous group of conditions affects different parts of the nervous system and presents …

New horizons in diabetic neuropathy: mechanisms, bioenergetics, and pain

EL Feldman, KA Nave, TS Jensen, DLH Bennett - Neuron, 2017 - cell.com
Pre-diabetes and diabetes are a global epidemic, and the associated neuropathic
complications create a substantial burden on both the afflicted patients and society as a …

Microvascular dysfunction in diabetes mellitus and cardiometabolic disease

WB Horton, EJ Barrett - Endocrine reviews, 2021 - academic.oup.com
This review takes an inclusive approach to microvascular dysfunction in diabetes mellitus
and cardiometabolic disease. In virtually every organ, dynamic interactions between the …

[HTML][HTML] Association between the prognostic nutritional index and chronic microvascular complications in patients with type 2 diabetes mellitus

G Aktas - Journal of Clinical Medicine, 2023 - mdpi.com
The prognostic nutritional index (PNI) is associated with inflammatory conditions. Since type
2 diabetes mellitus (T2DM) and its microvascular complications produce a significant …

Evaluating all potential oral complications of diabetes mellitus

MJL Verhulst, BG Loos, VEA Gerdes… - Frontiers in …, 2019 - frontiersin.org
Diabetes mellitus (DM) is associated with several microvascular and macrovascular
complications, such as retinopathy, nephropathy, neuropathy, and cardiovascular diseases …

Inflammatory mechanisms in the pathophysiology of diabetic peripheral neuropathy (DN)—new aspects

P Baum, KV Toyka, M Blüher, J Kosacka… - International Journal of …, 2021 - mdpi.com
The pathogenesis of diabetic neuropathy is complex, and various pathogenic pathways
have been proposed. A better understanding of the pathophysiology is warranted for …

The impact of oxidative stress on testicular function and the role of antioxidants in improving it: a review

N Asadi, M Bahmani, A Kheradmand… - Journal of clinical …, 2017 - pmc.ncbi.nlm.nih.gov
Oxidative stress is an important factor for development of male infertility because of very high
rate of cell division and mitochondrial oxygen consumption in testicular tissue as well as …

Chronic diabetes complications: the need to move beyond classical concepts

D Mauricio, N Alonso, M Gratacòs - Trends in Endocrinology & Metabolism, 2020 - cell.com
Chronic-diabetes-related complications simultaneously compromise both the micro-and
macrovascular trees, with target organs considered as the paradigm of large vessel injury …

[HTML][HTML] Vascular complications of diabetes: mechanisms of injury and protective factors

C Rask-Madsen, GL King - Cell metabolism, 2013 - cell.com
In patients with diabetes, atherosclerosis is the main reason for impaired life expectancy,
and diabetic nephropathy and retinopathy are the largest contributors to end-stage renal …