Enantioselective separation techniques in forensic analysis and clinical toxicology

FP Busardò, A Tini, AFL Faro, G Basile, T Farkas… - TrAC Trends in …, 2024 - Elsevier
Enantioselective analysis is more demanding compared to non-enantioselective one from
the viewpoint of time, effort and resources. At the same time if correctly designed it may bring …

Development of an enantioselective high-performance liquid chromatography-tandem mass spectrometry method for the quantitative determination of methorphan …

AFL Faro, D Berardinelli, G Sprega, A Tini… - … of Pharmaceutical and …, 2023 - Elsevier
In the present work an isocratic enantioselective high-performance liquid chromatography-
tandem mass spectrometry (LC-MS/MS) method was developed for the separation and …

Microsampling and enantioselective liquid chromatography coupled to mass spectrometry for chiral bioanalysis of novel psychoactive substances

M Protti, I Varfaj, A Carotti, D Tedesco, M Bartolini… - Talanta, 2023 - Elsevier
In this paper, the development of efficient enantioselective HPLC methods for the analysis of
five benzofuran-substituted phenethylamines, two substituted tryptamines, and three …

Sensitive detection of dextromethorphan hydrobromide based on portable Raman spectrometer and CuO@ AgNPs nano composite SERS substrate

B Yang, J Liu, F Zhang, Y Wang, X Liu, S Niu… - … Acta Part A: Molecular …, 2024 - Elsevier
A highly sensitive surface-enhanced Raman spectroscopy approach was established for the
detection of dextromethorphan hydrobromide (DXM) utilizing nano CuO modified silver …

Chiral dualism as a unifying principle in molecular biophysics

EV Malyshko, EV Semenova, OE Bagrova… - Biophysica, 2021 - mdpi.com
The origin and potential role of chiral asymmetry remain one of the most exciting issues in
biology. In this paper we review the chirality of biological macromolecules, starting at the …

Potential transducers based man-tailored biomimetic sensors for selective recognition of dextromethorphan as an antitussive drug

EH El-Naby, AH Kamel - Materials Science and Engineering: C, 2015 - Elsevier
A biomimetic potentiometric sensor for specific recognition of dextromethorphan (DXM), a
drug classified according to the Drug Enforcement Administration (DEA) as a “drug of …

Development of a novel enantioselective high-performance liquid chromatography–mass spectrometry method for the differentiation of dextro-and levo-methorphan …

S Jorbenadze, T Khatiashvili, A Chelidze… - … of Pharmaceutical and …, 2024 - Elsevier
Recently we proposed an isocratic enantioselective high-performance liquid
chromatography-tandem mass spectrometry (LC–MS/MS) method for the separation and …

Source identification of heroin by rapid detection of organic impurities using direct analysis in real time with high-resolution mass spectrometry and multivariate …

X Cui, R Lian, J Chen, C Ni, C Liang, G Chen… - Microchemical …, 2019 - Elsevier
Direct analysis in real time coupled with high-resolution mass spectrometry (DART-HRMS)
followed by multivariate statistical analysis has been successfully applied to infer the …

Purity and adulterant analysis of some recent drug seizures in Italy.

S Pichini, FP Busardò, A Gregori, P Berretta… - Drug testing and …, 2016 - europepmc.org
The data collected in this study describe an initial attempt to systematically introduce the
qualitative and quantitative analysis of adulterants present in seized street drugs in Italy with …

Chiral analysis of methorphan in opiate-overdose related deaths by using capillary electrophoresis

A Bertaso, G Musile, R Gottardo, C Seri… - … of Chromatography B, 2015 - Elsevier
An enantioselective CE-based determination of methorphan and its main metabolites in
blood is described. Enantiomeric separations were carried out in 50 cm× 50 μm (ID) …