Peptide–nanoparticle conjugates: a next generation of diagnostic and therapeutic platforms?
Peptide–nanoparticle conjugates (PNCs) have recently emerged as a versatile tool for
biomedical applications. Synergism between the two promising classes of materials allows …
biomedical applications. Synergism between the two promising classes of materials allows …
Advances in the therapeutic delivery and applications of functionalized Pluronics: A critical review
Abstract Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …
structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. Pluronics …
Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer
Despite decades of study, the molecular mechanisms and selectivity of the biomolecular
components of honeybee (Apis mellifera) venom as anticancer agents remain largely …
components of honeybee (Apis mellifera) venom as anticancer agents remain largely …
Precision medicine by designer interference peptides: applications in oncology and molecular therapeutics
In molecular cancer therapeutics only 10% of known cancer gene products are targetable
with current pharmacological agents. Major oncogenic drivers, such as MYC and KRAS …
with current pharmacological agents. Major oncogenic drivers, such as MYC and KRAS …
Tumor penetrating peptides inhibiting MYC as a potent targeted therapeutic strategy for triple-negative breast cancers
Overexpression of MYC oncogene is highly prevalent in many malignancies such as
aggressive triple-negative breast cancers (TNBCs) and it is associated with very poor …
aggressive triple-negative breast cancers (TNBCs) and it is associated with very poor …
Recent advances in peptide-based therapeutic strategies for breast cancer treatment
Breast cancer is the leading cause of cancer-related fatalities in female worldwide. Effective
therapies with low side effects for breast cancer treatment and prevention are, accordingly …
therapies with low side effects for breast cancer treatment and prevention are, accordingly …
[HTML][HTML] Waking up dormant tumor suppressor genes with zinc fingers, TALEs and the CRISPR/dCas9 system
The aberrant epigenetic silencing of tumor suppressor genes (TSGs) plays a major role
during carcinogenesis and regaining these dormant functions by engineering of sequence …
during carcinogenesis and regaining these dormant functions by engineering of sequence …
From seabed to bedside: A review on promising marine anticancer compounds
The marine environment represents an outstanding source of antitumoral compounds and,
at the same time, remains highly unexplored. Organisms living in the sea synthesize a wide …
at the same time, remains highly unexplored. Organisms living in the sea synthesize a wide …
Peptides, proteins and nanotechnology: A promising synergy for breast cancer targeting and treatment
Introduction The use of nanoparticles for breast cancer targeting and treatment has become
a reality. They are safe and possess interesting peculiarities such as the unspecific …
a reality. They are safe and possess interesting peculiarities such as the unspecific …
Actively targeted nanomedicines in breast cancer: from pre-clinal investigation to clinic
Simple Summary Despite all the efforts and advances made in the treatment of breast
cancer, this pathology continues to be one of the main causes of cancer death in women …
cancer, this pathology continues to be one of the main causes of cancer death in women …